Category: pyrazoles-derivatives

Product Details of 814-94-8. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: Tin(II) oxalate, is researched, Molecular C2O4Sn, CAS is 814-94-8, about Morphology-controlled synthesis of Sn3O4 nanowires for enhanced solar-light driven photocatalytic H2 production. Author is Mone, Parashar; Mardikar, Satish; Balgude, Sagar.

Herein, present paper we have successfully demonstrated a facile hydrothermal synthesis of Sn3O4 nanowires for efficient hydrogen production under solar light irradiation The triclinic phase and chem. composition were accomplished by XRD and XPS resp. The morphol. characterization using FESEM revealed nanowire-like morphol. of the as-synthesized material. The optical band gap for Sn3O4 nanowires was found to be 2.55 eV. In view of the band structure in the visible region, the photocatalytic activity of the as-synthesized Sn3O4 photocatalyst for the hydrogen production via. H2S splitting under natural sunlight has been investigated. The Sn3O4 nanowires demonstrated excellent photocatalytic activity (3933.65μmol/0.5g/h) for hydrogen production Improved photocatalytic activity was attributed to the morphol. and crystallinity of as-synthesized Sn3O4 nanowires. Based on results obtained possible mechanism for the photocatalytic hydrogen evolution was illustrated.

《Morphology-controlled synthesis of Sn3O4 nanowires for enhanced solar-light driven photocatalytic H2 production》 provides a strategy for the preparation of materials with excellent comprehensive properties, which is conducive to broaden the application field of this compound(Tin(II) oxalate)Product Details of 814-94-8.

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The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 3-Hydroxy-3-phenylpropanenitrile( cas:17190-29-3 ) is researched.Formula: C9H9NO.Koenig, Thomas M.; Mitchell, David published the article 《A convenient method for preparing enantiomerically pure norfluoxetine, fluoxetine and tomoxetine》 about this compound( cas:17190-29-3 ) in Tetrahedron Letters. Keywords: norfluoxetine enantiomeric preparation; fluoxetine enantiomeric preparation; tomoxetine enantiomeric preparation. Let’s learn more about this compound (cas:17190-29-3).

A convenient synthesis for enantiomers of norfluoxetine (I; R = 4-F3C, R1 = H), fluoxetine (I; R = F3C, R1 = Me) and tomoxetine (I: R = R1 = Me) is described. All final products were derived from 3-phenyl-3-hydroxypropylamine, prepared in 2 steps from PhCHO and acetonitrile.

This compound(3-Hydroxy-3-phenylpropanenitrile)Formula: C9H9NO was discussed at the molecular level, the effects of temperature and reaction time on the properties of the compound were discussed, and the optimum reaction conditions were selected.

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Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

Recommanded Product: 25956-17-6. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: Sodium 6-hydroxy-5-((2-methoxy-5-methyl-4-sulfonatophenyl)diazenyl)naphthalene-2-sulfonate, is researched, Molecular C18H14N2Na2O8S2, CAS is 25956-17-6, about Exploring rapid photocatalytic degradation of organic pollutants with porous CuO nanosheets: Synthesis, dye removal, and kinetic studies at room temperature. Author is Nazim, Mohammed; Khan, Aftab Aslam Parwaz; Asiri, Abdullah M.; Kim, Jae Hyun.

In this work, we report the facile, environmentally friendly, room-temperature (RT) synthesis of porous CuO nanosheets and their application as a photocatalyst to degrade an organic pollutant/food dye using NaBH4 as the reducing agent in an aqueous medium. Ultrahigh-resolution field effect SEM images of CuO displayed a broken nanosheet-like (a length of ~160 nm, a width of ~65 nm) morphol., and the lattice strain was estimated to be ~1.24 x 10-3 using the Williamson-Hall anal. of X-ray diffraction plots. Owing to the strong quantum size confinement effect, CuO nanosheets resulted in an optical energy band gap of ~1.92 eV, measured using Tauc plots of the UV-visible (UV-vis) spectrum, resulting in excellent photocatalytic efficiency. The RT synthesized CuO catalyst showed a high Brunauer-Emmet-Teller surface area of 30.88 ± 0.2313 m2/g (a correlation coefficient of 0.99972) with an average Barrett-Joyner-Halenda pore size of ~20.385 nm. The obtained porous CuO nanosheets exhibited a high crystallinity of 73.5% with a crystallite size of ~12 nm and was applied as an efficient photocatalyst for degradation of the organic pollutant/food dye, Allura Red AC (AR) dye, as monitored by UV-vis spectrophotometric anal. and evidenced by a color change from red to colorless. From UV-vis spectra, CuO nanosheets exhibited an efficient and ultrafast photocatalytic degradation efficiency of ~96.99% for the AR dye in an aqueous medium within 6 min at RT. According to the Langmuir-Hinshelwood model, photodegradation reaction kinetics followed a pseudo-first-order reaction with a rate constant of k = 0.524 min-1 and a half-life (t1/2) of 2.5 min for AR dye degradation in the aqueous medium. The CuO nanosheets showed an outstanding recycling ability for AR degradation and would be highly favorable and an efficient catalyst due to the synergistic effect of high adsorption capability and photodegradation of the food dye.

This compound(Sodium 6-hydroxy-5-((2-methoxy-5-methyl-4-sulfonatophenyl)diazenyl)naphthalene-2-sulfonate)Recommanded Product: 25956-17-6 was discussed at the molecular level, the effects of temperature and reaction time on the properties of the compound were discussed, and the optimum reaction conditions were selected.

Reference:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

Category: pyrazoles-derivatives. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: Sodium 6-hydroxy-5-((2-methoxy-5-methyl-4-sulfonatophenyl)diazenyl)naphthalene-2-sulfonate, is researched, Molecular C18H14N2Na2O8S2, CAS is 25956-17-6, about NiFe2O4-rGO/ionic liquid modified carbon paste electrode: An amplified electrochemical sensitive sensor for determination of Sunset Yellow in the presence of Tartrazine and Allura Red. Author is Darabi, Rozhin; Shabani-Nooshabadi, Mehdi.

In this paper, using a carbon paste electrode (CPE) modified with 1-ethyl-3-methylimidazolium chloride as an ionic liquid (IL) and NiFe2O4-rGO nanocomposite (IL/NiFe2O4/rGO/CPE), a sensitive and effective electrochem. sensor is applied to analyze Sunset Yellow. The X-ray diffraction (XRD), SEM (SEM) with Energy Dispersive X-Ray Anal. (EDX) and Fourier-transform IR spectroscopy (FTIR) are employed to characterize the synthesized NiFe2O4-rGO nanocomposite. The oxidation peak currents of colorants were obtained by CV and DPV techniques; and as a result, the two linear ranges from 0.05 to 30μM (R2 = 0.9939) and 30 to 500μM (R2 = 0.9953) along with LOD of 0.03μM for Sunset Yellow is obtained. The proposed sensor is successfully applied to determine the Sunset Yellow, Tartrazine and Allura Red in PBS (pH 3). The IL/NiFe2O4/rGO/CPE displays a high performance for anal. of these dyes in hair shampoo and an orange juice as real samples with acceptable results.

This compound(Sodium 6-hydroxy-5-((2-methoxy-5-methyl-4-sulfonatophenyl)diazenyl)naphthalene-2-sulfonate)Category: pyrazoles-derivatives was discussed at the molecular level, the effects of temperature and reaction time on the properties of the compound were discussed, and the optimum reaction conditions were selected.

Reference:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

HPLC of Formula: 25956-17-6. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: Sodium 6-hydroxy-5-((2-methoxy-5-methyl-4-sulfonatophenyl)diazenyl)naphthalene-2-sulfonate, is researched, Molecular C18H14N2Na2O8S2, CAS is 25956-17-6, about Development of a biosponge based on Luffa cylindrica and crosslinked chitosan for Allura red AC adsorption. Author is Schio, Rejiane R.; Goncalves, Janaina O.; Mallmann, Evandro S.; Pinto, Diana; Dotto, Guilherme L..

A new bioadsorbent from Luffa cylindrica and cross-linked chitosan was proposed in the present study. Luffa was used as a natural support medium for chitosan crosslinked with glutaraldehyde (LCsG) and epichlorohydrin (LCsE). Biosponges were applied to remove Allura red from aqueous solutions LCsG and LCsE were produced using different concentrations of chitosan (1%, 3% and 5% (m v-1)) and crosslinking agents (0.5%, 1.0% and 1.5% (v v-1)). Based on the FT-IR spectra, functional groups characteristic of chitosan crosslinked with glutaraldehyde and epichlorohydrin confirmed the crosslinking. In addition, the biosorbent revealed highly efficient functional groups and morphol. with irregularities favorable for adsorption. It was found that the increase in the percentage of glutaraldehyde and epichlorohydrin increased the sample’s swelling degree, and the degree of crosslinking was greater than 80% for all LCsG. The results regarding the degree of swelling and degree of crosslinking corroborated with the evaluation of the biosponge’s adsorptive potential. The Sips model predicted the equilibrium isotherms, with a maximum adsorption capacity of 89.05 mg g-1 for LCsG and 60.91 mg g-1 for LCsE. The new procedure was successful. Luffa was excellent support for chitosan, resulting in an attractive, low-cost bioadsorbent, preventing renewable sources.

This compound(Sodium 6-hydroxy-5-((2-methoxy-5-methyl-4-sulfonatophenyl)diazenyl)naphthalene-2-sulfonate)HPLC of Formula: 25956-17-6 was discussed at the molecular level, the effects of temperature and reaction time on the properties of the compound were discussed, and the optimum reaction conditions were selected.

Reference:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov’t, Research Support, U.S. Gov’t, Non-P.H.S., Journal of the American Chemical Society called Aqueous Benzylic C-H Trifluoromethylation for Late-Stage Functionalization, Author is Guo, Shuo; AbuSalim, Deyaa I.; Cook, Silas P., which mentions a compound: 1300746-79-5, SMILESS is F[C-](F)([Cu+]1[N]2=C3C4=[N]1C=CC=C4C=CC3=CC=C2)F, Molecular C13H8CuF3N2, Electric Literature of C13H8CuF3N2.

The installation of trifluoromethyl groups has become an essential step across a number of industries such as agrochems., drug discovery, and materials. Consequently, the rapid introduction of this critical functional group in a predictable fashion would benefit current practitioners in those fields. This communication describes a mild trifluoromethylation of benzylic C-H bonds with high selectivity for the least hindered hydrogen atom. The reaction provides monotrifluoromethylation and proceeds in an environmentally friendly acetone/water solvent system. The method can be used to install benzylic trifluoromethyl groups on highly functionalized drug mols.

This compound((1,10-Phenanthroline)(trifluoromethyl)copper(I))Electric Literature of C13H8CuF3N2 was discussed at the molecular level, the effects of temperature and reaction time on the properties of the compound were discussed, and the optimum reaction conditions were selected.

Reference:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

Wehn, Paul M.; Rizzi, James P.; Dixon, Darryl D.; Grina, Jonas A.; Schlachter, Stephen T.; Wang, Bin; Xu, Rui; Yang, Hanbiao; Du, Xinlin; Han, Guangzhou; Wang, Keshi; Cao, Zhaodan; Cheng, Tzuling; Czerwinski, Robert M.; Goggin, Barry S.; Huang, Heli; Halfmann, Megan M.; Maddie, Melissa A.; Morton, Emily L.; Olive, Sarah R.; Tan, Huiling; Xie, Shanhai; Wong, Tai; Josey, John A.; Wallace, Eli M. published the article 《Design and Activity of Specific Hypoxia-Inducible Factor-2α (HIF-2α) Inhibitors for the Treatment of Clear Cell Renal Cell Carcinoma: Discovery of Clinical Candidate (S)-3-((2,2-Difluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1H-inden-4-yl)oxy)-5-fluorobenzonitrile (PT2385)》. Keywords: indene preparation HIF2 inhibitor renal cell carcinoma treatment.They researched the compound: (1,10-Phenanthroline)(trifluoromethyl)copper(I)( cas:1300746-79-5 ).Electric Literature of C13H8CuF3N2. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:1300746-79-5) here.

HIF-2α, a member of the HIF family of transcription factors, is a key oncogenic driver in cancers such as clear cell renal cell carcinoma (ccRCC). A signature feature of these cancers is the overaccumulation of HIF-2α protein, often by inactivation of the E3 ligase VHL (von Hippel-Lindau). Herein the authors disclose their structure based drug design (SBDD) approach that culminated in the identification of PT2385, the first HIF-2α antagonist to enter clin. trials. Highlights include the use of a putative n → π*Ar interaction to guide early analog design, the conformational restriction of an essential hydroxyl moiety, and the remarkable impact of fluorination near the hydroxyl group. Evaluation of select compounds from two structural classes in a sequence of PK/PD, efficacy, PK, and metabolite profiling identified I (PT2385, luciferase EC50 = 27 nM) as the clin. candidate. Finally, a retrospective crystallog. anal. describes the structural perturbations necessary for efficient antagonism.

This compound((1,10-Phenanthroline)(trifluoromethyl)copper(I))Electric Literature of C13H8CuF3N2 was discussed at the molecular level, the effects of temperature and reaction time on the properties of the compound were discussed, and the optimum reaction conditions were selected.

Reference:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: 3-Hydroxy-3-phenylpropanenitrile, is researched, Molecular C9H9NO, CAS is 17190-29-3, about P(RNCH2CH2)3N-Catalyzed Synthesis of β-Hydroxy Nitriles, the main research direction is proazaphosphatrane catalyst reaction nitrile aldehyde ketone; hydroxy nitrile preparation.Product Details of 17190-29-3.

Successful synthesis of β-hydroxy nitriles in very good to excellent yields from aldehydes and ketones in a simple reaction that is promoted by strong nonionic bases of the title type is reported. The reaction occurs in the presence of magnesium salts which activate the carbonyl group and stabilizes the enolate thus produced. E.g., reaction of MeCN with acetone in presence of a proazaphosphatrane and MgSO4 gave 94% HOCMe2CH2CN.

This compound(3-Hydroxy-3-phenylpropanenitrile)Product Details of 17190-29-3 was discussed at the molecular level, the effects of temperature and reaction time on the properties of the compound were discussed, and the optimum reaction conditions were selected.

Reference:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Huang, Yaozeng; Liao, Yi researched the compound: 3-Hydroxy-3-phenylpropanenitrile( cas:17190-29-3 ).Application of 17190-29-3.They published the article 《Synthetic applications of elementoorganic compounds of group 15 and 16. 85. Pentaalkyl stiboranes. 1. Synthesis of homobenzylic alcohols, homoallylic alcohols, homoallylic alcohols, ethyl 5-aryl-5-hydroxy-2-pentenoates, and β-hydroxypropionic acid derivatives via pentaalkylstiboranes》 about this compound( cas:17190-29-3 ) in Journal of Organic Chemistry. Keywords: stiborane alkyl preparation reaction aldehyde; alc homobenzylic homoallylic; pentenoate hydroxy; aldehyde aromatic reaction pentaalkylstiborane. We’ll tell you more about this compound (cas:17190-29-3).

Although pentaalkylstiboranes have long been known, their applications in organic synthesis have not been exploited. Treating [Bu3SbCH2E]+ X- (E = Ph, vinyl, CH:CHCO2Et, CO2Et, cyano; X = Br, iodo, BPh4) with RLi (R = Bu, Me3C, Ph) give pentaalkylstiboranes, Bu3Sb(R)CH2E, which react with aromatic aldehydes to give, after subsequent hydrolysis, homobenzylic and homoallylic alcs., Et 5-aryl-5-hydroxy-2-pentenoates, Et β-aryl-β-hydroxypropionates, and β-aryl-β-hydroxypropionitriles, resp., in good-to-excellent yields. The reaction is chemoselective for aldehydes.

This compound(3-Hydroxy-3-phenylpropanenitrile)Application of 17190-29-3 was discussed at the molecular level, the effects of temperature and reaction time on the properties of the compound were discussed, and the optimum reaction conditions were selected.

Reference:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

Related Products of 25956-17-6. The fused heterocycle is formed by combining a benzene ring with a single heterocycle, or two or more single heterocycles. Compound: Sodium 6-hydroxy-5-((2-methoxy-5-methyl-4-sulfonatophenyl)diazenyl)naphthalene-2-sulfonate, is researched, Molecular C18H14N2Na2O8S2, CAS is 25956-17-6, about Designing refractive index fluids using the Kramers-Kronig relations. Author is Sai, Tianqi; Saba, Matthias; Dufresne, Eric R.; Steiner, Ullrich; Wilts, Bodo D..

For a number of optical applications, it is advantageous to precisely tune the refractive index of a liquid Here, we harness a well-established concept in optics for this purpose. The Kramers-Kronig relation provides a phys. connection between the spectral variation of the (real) refractive index and the absorption coefficient In particular, a sharp spectral variation of the absorption coefficient gives rise to either an enhancement or reduction of the refractive index in the spectral vicinity of this variation. By using bright commodity dyes that fulfil this absorption requirement, we demonstrate the use of the Kramers-Kronig relation to predictively obtain refractive index values in water solutions that are otherwise only attained with toxic specialised liquids

This compound(Sodium 6-hydroxy-5-((2-methoxy-5-methyl-4-sulfonatophenyl)diazenyl)naphthalene-2-sulfonate)Related Products of 25956-17-6 was discussed at the molecular level, the effects of temperature and reaction time on the properties of the compound were discussed, and the optimum reaction conditions were selected.

Reference:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics