{"id":9983,"date":"2022-10-13T03:03:03","date_gmt":"2022-10-12T19:03:03","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=9983"},"modified":"2022-10-13T03:03:03","modified_gmt":"2022-10-12T19:03:03","slug":"danagulyan-gevorg-g-s-team-published-research-in-chemistry-of-heterocyclic-compounds-new-york-ny-united-states-in-2015-cas-15366-34-4","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=9983","title":{"rendered":"Danagulyan, Gevorg G.’s team published research in Chemistry of Heterocyclic Compounds (New York, NY, United States) in 2015 | CAS: 15366-34-4"},"content":{"rendered":"

Electric Literature of C5H6N2O2<\/a>In 2015 ,\u300aSynthesis of N- and C-azolyl-substituted pyrazolo[1,5-a]pyrimidines by recyclization of pyrimidinium salts\u300b appeared in Chemistry of Heterocyclic Compounds (New York, NY, United States). The author of the article were Danagulyan, Gevorg G.; Tumanyan, Araksya K.; Attaryan, Oganes S.; Tamazyan, Rafael A.; Danagulyan, Anna G.; Ayvazyan, Armen G.. The article conveys some information:<\/p>\n

The authors studied a reaction of 2-(ethoxycarbonyl)methyl-1,4,6-trimethylpyrimidinium iodide with hydrazides of N-azolyl- and C-pyrazole-substituted carboxylic acids, which were synthesized from the resp. esters and hydrazine hydrate. This reaction was shown to result in recyclization and formation of Et 2-(pyrazolylalkyl)- and 2-(azolylalkyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxylates. Besides pyrazolopyrimidines, the separation of reaction mixture provided in some cases also another recyclization product, 2-hydroxy-5,7-dimethylpyrazolo[1,5-a]pyrimidine. The synthesis of the target compounds was achieved using 2-(2-ethoxy-2-oxoethyl)-1,4,6-trimethylpyrimidinium iodide and 1H-pyrazole-3-carboxylic acid hydrazide, 1H-pyrazole-1-acetic acid hydrazide, 1H-1,2,4-triazole-1-acetic acid hydrazide as key reactants. The title compounds thus formed included (pyrazolyl)pyrazolo[1,5-a]pyrimidine derivatives and (triazolyl)pyrazolo[1,5-a]pyrimidine derivatives In the part of experimental materials, we found many familiar compounds, such as Methyl 1H-pyrazole-3-carboxylate(cas: 15366-34-4Electric Literature of C5H6N2O2<\/a>)<\/p>\n

Methyl 1H-pyrazole-3-carboxylate(cas: 15366-34-4) belongs to pyrazoles. Pyrazole derivatives have been reported to exhibit a wide range of applications in medicinal chemistry and pharmacology. A large number of drugs incorporating pyrazole structure have been utilized as partial agonists for nicotinic acid receptors, antidepressants, antimicrobial agents, antiviral agents, and antifungal agents solely or along with the combination of other structural motifs.Electric Literature of C5H6N2O2<\/a><\/p>\n

Referemce:
Pyrazole – Wikipedia<\/a>,
Pyrazoles – an overview | ScienceDirect Topics<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Methyl 1H-pyrazole-3-carboxylate(cas: 15366-34-4) belongs to pyrazoles. Pyrazole derivatives have been reported to exhibit a wide range of applications in medicinal chemistry and pharmacology. A large number of drugs incorporating pyrazole structure have been utilized as partial agonists for nicotinic acid receptors, antidepressants, antimicrobial agents, antiviral agents, and antifungal agents solely or along with the combination of other structural motifs.Electric Literature of C5H6N2O2<\/a><\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[174,131],"tags":[128],"class_list":["post-9983","post","type-post","status-publish","format-standard","hentry","category-15366-34-4","category-pyrazoles-derivatives","tag-100-200"],"yoast_head":"\nDanagulyan, Gevorg G.'s team published research in Chemistry of Heterocyclic Compounds (New York, NY, United States) in 2015 | CAS: 15366-34-4 | pyrazoles-derivatives<\/title>\n<meta name=\"description\" content=\"Electric Literature of C5H6N2O2In 2015 ,\u300aSynthesis of N- and C-azolyl-substituted pyrazolo[1,5-a]pyrimidines by recyclization of pyrimidinium salts\u300b appeared in Chemistry of Heterocyclic Compounds (New York, NY, United States). 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