{"id":9973,"date":"2022-10-12T07:02:02","date_gmt":"2022-10-11T23:02:02","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=9973"},"modified":"2022-10-12T07:02:02","modified_gmt":"2022-10-11T23:02:02","slug":"lucas-simon-c-cs-team-published-research-in-journal-of-organic-chemistry-in-2015-12-18-1046832-21-6","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=9973","title":{"rendered":"Lucas, Simon C C&#8217;s team published research in Journal of Organic Chemistry  in 2015-12-18 | 1046832-21-6"},"content":{"rendered":"<p>Lucas, Simon C. C.; Moore, Jane E.; Donald, Craig S.; Hawkins, Janet L. published the artcile< Synthesis of 4-Arylthieno[2,3-b]pyridines and 4-Aminothieno[2,3-b]pyridines via a Regioselective Bromination of Thieno[2,3-b]pyridine>,  <a href=\"https:\/\/www.ambeed.com\/products\/1046832-21-6.html\">HPLC of Formula: 1046832-21-6<\/a>,  the main research area is  thienopyridine oxidation regioselective bromination; bromothienopyridine regioselective preparation Suzuki Miyaura Buchwald cross coupling; aryl thienopyridine preparation; amino thienopyridine preparation.<\/p>\n<p>The first regioselective, mild bromination of thieno[2,3-b]pyridine is described herein. The reaction proceeds with selectivity toward the 4-position (87% isolated yield). Subsequent cross-coupling reactions proceed in excellent yields and demonstrate the potential of 4-bromothieno[2,3-b]pyridine as a building block for use in drug discovery research.<\/p>\n<p>Journal of Organic Chemistry published new progress about Boronic acids, esters Role: RCT (Reactant), RACT (Reactant or Reagent). 1046832-21-6 belongs to class pyrazoles-derivatives, and the molecular formula is C11H19BN2O2, <a href=\"https:\/\/www.ambeed.com\/products\/1046832-21-6.html\">HPLC of Formula: 1046832-21-6<\/a>.<\/p>\n<p>Referemce:<br \/><a href=\"https:\/\/en.wikipedia.org\/wiki\/Pyrazole\">Pyrazole &#8211; Wikipedia<\/a>,<br \/><a href=\"https:\/\/www.sciencedirect.com\/topics\/chemistry\/pyrazoles\">Pyrazoles &#8211; an overview | ScienceDirect Topics<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Journal of Organic Chemistry published new progress about Boronic acids, esters Role: RCT (Reactant), RACT (Reactant or Reagent). 1046832-21-6 belongs to class pyrazoles-derivatives, and the molecular formula is C11H19BN2O2, <a href=\"https:\/\/www.ambeed.com\/products\/1046832-21-6.html\">HPLC of Formula: 1046832-21-6<\/a>.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[737,131],"tags":[716],"class_list":["post-9973","post","type-post","status-publish","format-standard","hentry","category-1046832-21-6","category-pyrazoles-derivatives","tag-m-w200-250"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Lucas, Simon C C&#039;s team published research in Journal of Organic Chemistry in 2015-12-18 | 1046832-21-6 | pyrazoles-derivatives<\/title>\n<meta name=\"description\" content=\"Lucas, Simon C. C.; Moore, Jane E.; Donald, Craig S.; Hawkins, Janet L. published the artcile&lt; Synthesis of 4-Arylthieno[2,3-b]pyridines and 4-Aminothieno[2,3-b]pyridines via a Regioselective Bromination of Thieno[2,3-b]pyridine&gt;, HPLC of Formula: 1046832-21-6, the main research area is thienopyridine oxidation regioselective bromination; bromothienopyridine regioselective preparation Suzuki Miyaura Buchwald cross coupling; aryl thienopyridine preparation; amino thienopyridine preparation.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=9973\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Lucas, Simon C C&#039;s team published research in Journal of Organic Chemistry in 2015-12-18 | 1046832-21-6 | pyrazoles-derivatives\" \/>\n<meta property=\"og:description\" content=\"Lucas, Simon C. C.; Moore, Jane E.; Donald, Craig S.; Hawkins, Janet L. published the artcile&lt; Synthesis of 4-Arylthieno[2,3-b]pyridines and 4-Aminothieno[2,3-b]pyridines via a Regioselective Bromination of Thieno[2,3-b]pyridine&gt;, HPLC of Formula: 1046832-21-6, the main research area is thienopyridine oxidation regioselective bromination; bromothienopyridine regioselective preparation Suzuki Miyaura Buchwald cross coupling; aryl thienopyridine preparation; amino thienopyridine preparation.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.pyrazoles-derivatives.com\/?p=9973\" \/>\n<meta property=\"og:site_name\" content=\"pyrazoles-derivatives\" \/>\n<meta property=\"article:published_time\" content=\"2022-10-11T23:02:02+00:00\" \/>\n<meta name=\"author\" content=\"Jessica.F\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jessica.F\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=9973\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=9973\",\"name\":\"Lucas, Simon C C's team published research in Journal of Organic Chemistry in 2015-12-18 | 1046832-21-6 | pyrazoles-derivatives\",\"isPartOf\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\"},\"datePublished\":\"2022-10-11T23:02:02+00:00\",\"author\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\"},\"description\":\"Lucas, Simon C. C.; Moore, Jane E.; Donald, Craig S.; Hawkins, Janet L. published the artcile< Synthesis of 4-Arylthieno[2,3-b]pyridines and 4-Aminothieno[2,3-b]pyridines via a Regioselective Bromination of Thieno[2,3-b]pyridine>, HPLC of Formula: 1046832-21-6, the main research area is thienopyridine oxidation regioselective bromination; bromothienopyridine regioselective preparation Suzuki Miyaura Buchwald cross coupling; aryl thienopyridine preparation; amino thienopyridine preparation.\",\"breadcrumb\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=9973#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.pyrazoles-derivatives.com\/?p=9973\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=9973#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"\u9996\u9875\",\"item\":\"https:\/\/www.pyrazoles-derivatives.com\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Lucas, Simon C C&#8217;s team published research in Journal of Organic Chemistry in 2015-12-18 | 1046832-21-6\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/\",\"name\":\"pyrazoles-derivatives\",\"description\":\"Several pyrazole derivatives possess important pharmacological activities and they have been proved useful materials in drug research. Pyrazole derivatives play an important role in antitumor agents.\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\",\"name\":\"Jessica.F\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"caption\":\"Jessica.F\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Lucas, Simon C C's team published research in Journal of Organic Chemistry in 2015-12-18 | 1046832-21-6 | pyrazoles-derivatives","description":"Lucas, Simon C. C.; Moore, Jane E.; Donald, Craig S.; Hawkins, Janet L. published the artcile< Synthesis of 4-Arylthieno[2,3-b]pyridines and 4-Aminothieno[2,3-b]pyridines via a Regioselective Bromination of Thieno[2,3-b]pyridine>, HPLC of Formula: 1046832-21-6, the main research area is thienopyridine oxidation regioselective bromination; bromothienopyridine regioselective preparation Suzuki Miyaura Buchwald cross coupling; aryl thienopyridine preparation; amino thienopyridine preparation.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.pyrazoles-derivatives.com\/?p=9973","og_locale":"en_US","og_type":"article","og_title":"Lucas, Simon C C's team published research in Journal of Organic Chemistry in 2015-12-18 | 1046832-21-6 | pyrazoles-derivatives","og_description":"Lucas, Simon C. C.; Moore, Jane E.; Donald, Craig S.; Hawkins, Janet L. published the artcile< Synthesis of 4-Arylthieno[2,3-b]pyridines and 4-Aminothieno[2,3-b]pyridines via a Regioselective Bromination of Thieno[2,3-b]pyridine>, HPLC of Formula: 1046832-21-6, the main research area is thienopyridine oxidation regioselective bromination; bromothienopyridine regioselective preparation Suzuki Miyaura Buchwald cross coupling; aryl thienopyridine preparation; amino thienopyridine preparation.","og_url":"https:\/\/www.pyrazoles-derivatives.com\/?p=9973","og_site_name":"pyrazoles-derivatives","article_published_time":"2022-10-11T23:02:02+00:00","author":"Jessica.F","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Jessica.F","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.pyrazoles-derivatives.com\/?p=9973","url":"https:\/\/www.pyrazoles-derivatives.com\/?p=9973","name":"Lucas, Simon C C's team published research in Journal of Organic Chemistry in 2015-12-18 | 1046832-21-6 | pyrazoles-derivatives","isPartOf":{"@id":"https:\/\/www.pyrazoles-derivatives.com\/#website"},"datePublished":"2022-10-11T23:02:02+00:00","author":{"@id":"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1"},"description":"Lucas, Simon C. C.; Moore, Jane E.; Donald, Craig S.; Hawkins, Janet L. published the artcile< Synthesis of 4-Arylthieno[2,3-b]pyridines and 4-Aminothieno[2,3-b]pyridines via a Regioselective Bromination of Thieno[2,3-b]pyridine>, HPLC of Formula: 1046832-21-6, the main research area is thienopyridine oxidation regioselective bromination; bromothienopyridine regioselective preparation Suzuki Miyaura Buchwald cross coupling; aryl thienopyridine preparation; amino thienopyridine preparation.","breadcrumb":{"@id":"https:\/\/www.pyrazoles-derivatives.com\/?p=9973#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.pyrazoles-derivatives.com\/?p=9973"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.pyrazoles-derivatives.com\/?p=9973#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"\u9996\u9875","item":"https:\/\/www.pyrazoles-derivatives.com\/"},{"@type":"ListItem","position":2,"name":"Lucas, Simon C C&#8217;s team published research in Journal of Organic Chemistry in 2015-12-18 | 1046832-21-6"}]},{"@type":"WebSite","@id":"https:\/\/www.pyrazoles-derivatives.com\/#website","url":"https:\/\/www.pyrazoles-derivatives.com\/","name":"pyrazoles-derivatives","description":"Several pyrazole derivatives possess important pharmacological activities and they have been proved useful materials in drug research. Pyrazole derivatives play an important role in antitumor agents.","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Person","@id":"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1","name":"Jessica.F","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/","url":"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g","contentUrl":"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g","caption":"Jessica.F"}}]}},"_links":{"self":[{"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=\/wp\/v2\/posts\/9973","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=9973"}],"version-history":[{"count":0,"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=\/wp\/v2\/posts\/9973\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=9973"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=9973"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=9973"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}