{"id":9953,"date":"2022-10-12T07:01:16","date_gmt":"2022-10-11T23:01:16","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=9953"},"modified":"2022-10-12T07:01:16","modified_gmt":"2022-10-11T23:01:16","slug":"osawa-akios-team-published-research-in-chemical-pharmaceutical-bulletin-in-1988-10-25-13808-65-6","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=9953","title":{"rendered":"Osawa, Akio’s team published research in Chemical & Pharmaceutical Bulletin in 1988-10-25 | 13808-65-6"},"content":{"rendered":"

Osawa, Akio; Kaiho, Terumitsu; Ito, Takashi; Okada, Mamiko; Kawabata, Chikako; Yamaguchi, Kentaro; Igeta, Hiroshi published the artcile< Reactions of N-aminopyrazoles with halogenating reagents and synthesis of 1,2,3-triazines>, Product Details of C9H7BrN2<\/a>, the main research area is triazine; pyrazolamine reaction halogenating agent; ring expansion aminopyrazole.<\/p>\n

Reactions of N-aminopyrazoles with halogenating reagents (Cl2, Br2, I2, BrCl, ICl, IBr, N-chlorosuccinimide, and N-bromosuccinimide) were examined Some of these reagents preferentially leas to oxidation of the amino group to give the corresponding 1,2,3-triazines as major products, while others mainly gave either or both of 1-amino-4-halopyrazoles and 5-halo-1,2,3-triazines as the result of halogenation of the 4-position of the pyrazole ring prior to the oxidation of the amino group. In some cases, the oxidation of the amino group and the halogenation of the pyrazole ring proceeded concurrently to form not only the unhalogenated triazines but also the 1-amino-4-halopyrazines and the 5-halotriazines. Various reagents and reaction conditions were explored to utilize the reaction for the synthesis of halogenated and unhalogenated 1,2,3-triazines.<\/p>\n

Chemical & Pharmaceutical Bulletin published new progress about Halogenation. 13808-65-6 belongs to class pyrazoles-derivatives, and the molecular formula is C9H7BrN2, Product Details of C9H7BrN2<\/a>.<\/p>\n

Referemce:
Pyrazole – Wikipedia<\/a>,
Pyrazoles – an overview | ScienceDirect Topics<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Chemical & Pharmaceutical Bulletin published new progress about Halogenation. 13808-65-6 belongs to class pyrazoles-derivatives, and the molecular formula is C9H7BrN2, Product Details of C9H7BrN2<\/a>.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[480,131],"tags":[716],"class_list":["post-9953","post","type-post","status-publish","format-standard","hentry","category-13808-65-6","category-pyrazoles-derivatives","tag-m-w200-250"],"yoast_head":"\nOsawa, Akio's team published research in Chemical & Pharmaceutical Bulletin in 1988-10-25 | 13808-65-6 | pyrazoles-derivatives<\/title>\n<meta name=\"description\" content=\"Osawa, Akio; Kaiho, Terumitsu; Ito, Takashi; Okada, Mamiko; Kawabata, Chikako; Yamaguchi, Kentaro; Igeta, Hiroshi published the artcile< Reactions of N-aminopyrazoles with halogenating reagents and synthesis of 1,2,3-triazines>, Product Details of C9H7BrN2, the main research area is triazine; pyrazolamine reaction halogenating agent; ring expansion aminopyrazole.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=9953\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Osawa, Akio's team published research in Chemical & Pharmaceutical Bulletin in 1988-10-25 | 13808-65-6 | pyrazoles-derivatives\" \/>\n<meta property=\"og:description\" content=\"Osawa, Akio; Kaiho, Terumitsu; Ito, Takashi; Okada, Mamiko; Kawabata, Chikako; Yamaguchi, Kentaro; Igeta, Hiroshi published the artcile< Reactions of N-aminopyrazoles with halogenating reagents and synthesis of 1,2,3-triazines>, Product Details of C9H7BrN2, the main research area is triazine; pyrazolamine reaction halogenating agent; ring expansion aminopyrazole.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.pyrazoles-derivatives.com\/?p=9953\" \/>\n<meta property=\"og:site_name\" content=\"pyrazoles-derivatives\" \/>\n<meta property=\"article:published_time\" content=\"2022-10-11T23:01:16+00:00\" \/>\n<meta name=\"author\" content=\"Jessica.F\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jessica.F\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=9953\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=9953\",\"name\":\"Osawa, Akio's team published research in Chemical & Pharmaceutical Bulletin in 1988-10-25 | 13808-65-6 | pyrazoles-derivatives\",\"isPartOf\":{\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/#website\"},\"datePublished\":\"2022-10-11T23:01:16+00:00\",\"author\":{\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\"},\"description\":\"Osawa, Akio; Kaiho, Terumitsu; Ito, Takashi; Okada, Mamiko; Kawabata, Chikako; Yamaguchi, Kentaro; Igeta, Hiroshi published the artcile< Reactions of N-aminopyrazoles with halogenating reagents and synthesis of 1,2,3-triazines>, Product Details of C9H7BrN2, the main research area is triazine; pyrazolamine reaction halogenating agent; ring expansion aminopyrazole.\",\"breadcrumb\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=9953#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.pyrazoles-derivatives.com\/?p=9953\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=9953#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"\u9996\u9875\",\"item\":\"http:\/\/www.pyrazoles-derivatives.com\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Osawa, Akio’s team published research in Chemical & Pharmaceutical Bulletin in 1988-10-25 | 13808-65-6\"}]},{\"@type\":\"WebSite\",\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/#website\",\"url\":\"http:\/\/www.pyrazoles-derivatives.com\/\",\"name\":\"pyrazoles-derivatives\",\"description\":\"Several pyrazole derivatives possess important pharmacological activities and they have been proved useful materials in drug research. 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