{"id":9730,"date":"2022-04-20T04:14:06","date_gmt":"2022-04-19T20:14:06","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=9730"},"modified":"2022-04-20T04:14:06","modified_gmt":"2022-04-19T20:14:06","slug":"the-effect-of-reaction-temperature-change-on-equilibrium-17190-29-3-3","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=9730","title":{"rendered":"The effect of  reaction temperature change on equilibrium 17190-29-3"},"content":{"rendered":"<p>Kawano, Yoshikazu; Kaneko, Nobuya; Mukaiyama, Teruaki published the article \u300aLewis base-catalyzed cyanomethylation of carbonyl compounds with (trimethylsilyl)acetonitrile\u300b.  Keywords: Lewis base catalyzed cyanomethylation carbonyl compound trimethylsilyl acetonitrile; lithium acetate catalyzed cyanomethylation carbonyl compound silyl acetonitrile.They  researched the compound: 3-Hydroxy-3-phenylpropanenitrile( cas:17190-29-3 ).<a href=\"https:\/\/www.ambeed.com\/products\/17190-29-3.html\">Category: pyrazoles-derivatives<\/a>. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:17190-29-3)  here.<\/p>\n<p>Catalytic cyanomethylation of various carbonyl compounds with (trimethylsilyl)acetonitrile (TMSCH2CN) in the presence of Lewis bases such as cesium or lithium acetate proceeded smoothly to afford the corresponding cyanomethylated adducts in good yields. Thus, AcOLi catalyzed cyanomethylation of PhCHO with Me3SiCH2CN in DMF at 0\u00b0 to room temperature followed by acid hydrolysis gave 98% PhCHOHCH2CN.<\/p>\n<p>\u300aLewis base-catalyzed cyanomethylation of carbonyl compounds with (trimethylsilyl)acetonitrile\u300b provides a strategy for the preparation of materials with excellent comprehensive properties, which is conducive to broaden the application field of this compound(3-Hydroxy-3-phenylpropanenitrile)<a href=\"https:\/\/www.ambeed.com\/products\/17190-29-3.html\">Category: pyrazoles-derivatives<\/a>.<\/p>\n<p>Reference:<br \/><a href=\"https:\/\/en.wikipedia.org\/wiki\/Pyrazole\">Pyrazole &#8211; Wikipedia<\/a>,<br \/><a href=\"https:\/\/www.sciencedirect.com\/topics\/chemistry\/pyrazoles\">Pyrazoles &#8211; an overview | ScienceDirect Topics<\/A><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u300aLewis base-catalyzed cyanomethylation of carbonyl compounds with (trimethylsilyl)acetonitrile\u300b provides a strategy for the preparation of materials with excellent comprehensive properties, which is conducive to broaden the application field of this compound(3-Hydroxy-3-phenylpropanenitrile)<a href=\"https:\/\/www.ambeed.com\/products\/17190-29-3.html\">Category: pyrazoles-derivatives<\/a>.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[723,131],"tags":[126],"class_list":["post-9730","post","type-post","status-publish","format-standard","hentry","category-17190-29-3","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>The effect of reaction temperature change on equilibrium 17190-29-3 | pyrazoles-derivatives<\/title>\n<meta name=\"description\" content=\"Kawano, Yoshikazu; Kaneko, Nobuya; Mukaiyama, Teruaki published the article \u300aLewis base-catalyzed cyanomethylation of carbonyl compounds with (trimethylsilyl)acetonitrile\u300b. Keywords: Lewis base catalyzed cyanomethylation carbonyl compound trimethylsilyl acetonitrile; lithium acetate catalyzed cyanomethylation carbonyl compound silyl acetonitrile.They researched the compound: 3-Hydroxy-3-phenylpropanenitrile( cas:17190-29-3 ).Category: pyrazoles-derivatives. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:17190-29-3) here.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=9730\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"The effect of reaction temperature change on equilibrium 17190-29-3 | pyrazoles-derivatives\" \/>\n<meta property=\"og:description\" content=\"Kawano, Yoshikazu; Kaneko, Nobuya; Mukaiyama, Teruaki published the article \u300aLewis base-catalyzed cyanomethylation of carbonyl compounds with (trimethylsilyl)acetonitrile\u300b. Keywords: Lewis base catalyzed cyanomethylation carbonyl compound trimethylsilyl acetonitrile; lithium acetate catalyzed cyanomethylation carbonyl compound silyl acetonitrile.They researched the compound: 3-Hydroxy-3-phenylpropanenitrile( cas:17190-29-3 ).Category: pyrazoles-derivatives. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. 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Keywords: Lewis base catalyzed cyanomethylation carbonyl compound trimethylsilyl acetonitrile; lithium acetate catalyzed cyanomethylation carbonyl compound silyl acetonitrile.They researched the compound: 3-Hydroxy-3-phenylpropanenitrile( cas:17190-29-3 ).Category: pyrazoles-derivatives. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. 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Pyrazole derivatives play an important role in antitumor agents.\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\",\"name\":\"Jessica.F\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"caption\":\"Jessica.F\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"The effect of reaction temperature change on equilibrium 17190-29-3 | pyrazoles-derivatives","description":"Kawano, Yoshikazu; Kaneko, Nobuya; Mukaiyama, Teruaki published the article \u300aLewis base-catalyzed cyanomethylation of carbonyl compounds with (trimethylsilyl)acetonitrile\u300b. Keywords: Lewis base catalyzed cyanomethylation carbonyl compound trimethylsilyl acetonitrile; lithium acetate catalyzed cyanomethylation carbonyl compound silyl acetonitrile.They researched the compound: 3-Hydroxy-3-phenylpropanenitrile( cas:17190-29-3 ).Category: pyrazoles-derivatives. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. 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Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. 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