{"id":9727,"date":"2022-04-20T04:14:06","date_gmt":"2022-04-19T20:14:06","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=9727"},"modified":"2022-04-20T04:14:06","modified_gmt":"2022-04-19T20:14:06","slug":"analyzing-the-synthesis-route-of-23077-42-1","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=9727","title":{"rendered":"Analyzing the synthesis route of 23077-42-1"},"content":{"rendered":"<p><a href=\"https:\/\/www.ambeed.com\/products\/23077-42-1.html\">Application In Synthesis of  4-Fluoro-1H-indole-3-carboxylic acid<\/a>. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: 4-Fluoro-1H-indole-3-carboxylic acid, is researched, Molecular C9H6FNO2, CAS is 23077-42-1, about Synthesis of cyclic chiral \u03b1-amino boronates by copper-catalyzed asymmetric dearomative borylation of indoles. Author is Chen, Lili; Shen, Jun-Jian; Gao, Qian; Xu, Senmiao.<\/p>\n<p>A copper(I)-catalyzed dearomative borylation of N-alkoxycarbonyl protected indole-3-carboxylates has been developed. The boron addition in this reaction occurred regioselectively at the 2-position of indoles followed by diastereoselective protonation, affording the corresponding stable cyclic chiral \u03b1-amino boronates (2-borylindolines) in moderate to good yields with excellent diastereo- and enantioselectivities. The product 2c could be used as a versatile precursor to undergo subsequent stereoselective transformations, delivering highly functionalized 2,3,3-trisubstituted chiral indolines.<\/p>\n<p>\u300aSynthesis of cyclic chiral \u03b1-amino boronates by copper-catalyzed asymmetric dearomative borylation of indoles\u300b provides a strategy for the preparation of materials with excellent comprehensive properties, which is conducive to broaden the application field of this compound(4-Fluoro-1H-indole-3-carboxylic acid)<a href=\"https:\/\/www.ambeed.com\/products\/23077-42-1.html\">Application In Synthesis of  4-Fluoro-1H-indole-3-carboxylic acid<\/a>.<\/p>\n<p>Reference:<br \/><a href=\"https:\/\/en.wikipedia.org\/wiki\/Pyrazole\">Pyrazole &#8211; Wikipedia<\/a>,<br \/><a href=\"https:\/\/www.sciencedirect.com\/topics\/chemistry\/pyrazoles\">Pyrazoles &#8211; an overview | ScienceDirect Topics<\/A><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u300aSynthesis of cyclic chiral \u03b1-amino boronates by copper-catalyzed asymmetric dearomative borylation of indoles\u300b provides a strategy for the preparation of materials with excellent comprehensive properties, which is conducive to broaden the application field of this compound(4-Fluoro-1H-indole-3-carboxylic acid)<a href=\"https:\/\/www.ambeed.com\/products\/23077-42-1.html\">Application In Synthesis of  4-Fluoro-1H-indole-3-carboxylic acid<\/a>.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[728,131],"tags":[126],"class_list":["post-9727","post","type-post","status-publish","format-standard","hentry","category-23077-42-1","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Analyzing the synthesis route of 23077-42-1 | pyrazoles-derivatives<\/title>\n<meta name=\"description\" content=\"Application In Synthesis of 4-Fluoro-1H-indole-3-carboxylic acid. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: 4-Fluoro-1H-indole-3-carboxylic acid, is researched, Molecular C9H6FNO2, CAS is 23077-42-1, about Synthesis of cyclic chiral \u03b1-amino boronates by copper-catalyzed asymmetric dearomative borylation of indoles. Author is Chen, Lili; Shen, Jun-Jian; Gao, Qian; Xu, Senmiao.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=9727\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Analyzing the synthesis route of 23077-42-1 | pyrazoles-derivatives\" \/>\n<meta property=\"og:description\" content=\"Application In Synthesis of 4-Fluoro-1H-indole-3-carboxylic acid. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: 4-Fluoro-1H-indole-3-carboxylic acid, is researched, Molecular C9H6FNO2, CAS is 23077-42-1, about Synthesis of cyclic chiral \u03b1-amino boronates by copper-catalyzed asymmetric dearomative borylation of indoles. 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The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: 4-Fluoro-1H-indole-3-carboxylic acid, is researched, Molecular C9H6FNO2, CAS is 23077-42-1, about Synthesis of cyclic chiral \u03b1-amino boronates by copper-catalyzed asymmetric dearomative borylation of indoles. 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Pyrazole derivatives play an important role in antitumor agents.\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\",\"name\":\"Jessica.F\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/weavatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/weavatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"caption\":\"Jessica.F\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Analyzing the synthesis route of 23077-42-1 | pyrazoles-derivatives","description":"Application In Synthesis of 4-Fluoro-1H-indole-3-carboxylic acid. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: 4-Fluoro-1H-indole-3-carboxylic acid, is researched, Molecular C9H6FNO2, CAS is 23077-42-1, about Synthesis of cyclic chiral \u03b1-amino boronates by copper-catalyzed asymmetric dearomative borylation of indoles. Author is Chen, Lili; Shen, Jun-Jian; Gao, Qian; Xu, Senmiao.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.pyrazoles-derivatives.com\/?p=9727","og_locale":"en_US","og_type":"article","og_title":"Analyzing the synthesis route of 23077-42-1 | pyrazoles-derivatives","og_description":"Application In Synthesis of 4-Fluoro-1H-indole-3-carboxylic acid. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: 4-Fluoro-1H-indole-3-carboxylic acid, is researched, Molecular C9H6FNO2, CAS is 23077-42-1, about Synthesis of cyclic chiral \u03b1-amino boronates by copper-catalyzed asymmetric dearomative borylation of indoles. 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The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: 4-Fluoro-1H-indole-3-carboxylic acid, is researched, Molecular C9H6FNO2, CAS is 23077-42-1, about Synthesis of cyclic chiral \u03b1-amino boronates by copper-catalyzed asymmetric dearomative borylation of indoles. 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