{"id":9684,"date":"2022-04-18T07:58:40","date_gmt":"2022-04-17T23:58:40","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=9684"},"modified":"2022-04-18T07:58:40","modified_gmt":"2022-04-17T23:58:40","slug":"now-is-the-time-for-you-to-know-the-truth-about-52287-51-1-4","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=9684","title":{"rendered":"Now Is The Time For You To Know The Truth About 52287-51-1"},"content":{"rendered":"<p>Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Article, Chemistry &#8211; An Asian Journal called Sequential SNAr Reaction\/Suzuki-Miyaura Coupling\/C-H Direct Arylations Approach for the Rapid Synthesis of Tetraaryl-Substituted Pyrazoles, Author is Morita, Taiki; Kobayashi, Daisuke; Matsumura, Keisuke; Johmoto, Kohei; Uekusa, Hidehiro; Fuse, Shinichiro; Takahashi, Takashi, which mentions a compound: 52287-51-1, SMILESS is BrC1=CC=C2OCCOC2=C1, Molecular C8H7BrO2, <a href=\"https:\/\/www.ambeed.com\/products\/52287-51-1.html\">Category: pyrazoles-derivatives<\/a>.<\/p>\n<p>The rapid synthesis of 1,3,4,5-tetraaryl-substituted pyrazoles I (R1 = CN, NO2; R2 = 4-CF3, 4-MeO, 2-Me; R3 = CN, Me, CO2Et; R4 = 4-O2NC6H4, naphthalen-2-yl, 2,3-dihydro-1,4-benzodioxin-6-yl, etc.) was achieved through a sequence of SNAr reaction\/Suzuki-Miyaura coupling\/Pd-catalyzed direct arylations that used 3-iodo-1H-pyrazole as a scaffold. Compounds I were synthesized in a straightforward manner with no extra synthetic steps, such as protection\/deprotection or the introduction of activating\/directing groups, using readily available substrates and reagents. The developed synthetic approach enabled the structurally diverse synthesis of multiaryl-substituted pyrazoles without using glovebox techniques.<\/p>\n<p>The article \u300aSequential SNAr Reaction\/Suzuki-Miyaura Coupling\/C-H Direct Arylations Approach for the Rapid Synthesis of Tetraaryl-Substituted Pyrazoles\u300b also mentions many details about this compound(52287-51-1)<a href=\"https:\/\/www.ambeed.com\/products\/52287-51-1.html\">Category: pyrazoles-derivatives<\/a>, you can pay attention to it or contacet with the author(sfuse@res.titech.ac.jp; sfuse@res.titech.ac.jp) to get more information.<\/p>\n<p>Reference:<br \/><a href=\"https:\/\/en.wikipedia.org\/wiki\/Pyrazole\">Pyrazole &#8211; Wikipedia<\/a>,<br \/><a href=\"https:\/\/www.sciencedirect.com\/topics\/chemistry\/pyrazoles\">Pyrazoles &#8211; an overview | ScienceDirect Topics<\/A><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The article \u300aSequential SNAr Reaction\/Suzuki-Miyaura Coupling\/C-H Direct Arylations Approach for the Rapid Synthesis of Tetraaryl-Substituted Pyrazoles\u300b also mentions many details about this compound(52287-51-1)<a href=\"https:\/\/www.ambeed.com\/products\/52287-51-1.html\">Category: pyrazoles-derivatives<\/a>, you can pay attention to it or contacet with the author(sfuse@res.titech.ac.jp; sfuse@res.titech.ac.jp) to get more information.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[725,131],"tags":[127],"class_list":["post-9684","post","type-post","status-publish","format-standard","hentry","category-52287-51-1","category-pyrazoles-derivatives","tag-m-w200-300"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Now Is The Time For You To Know The Truth About 52287-51-1 | pyrazoles-derivatives<\/title>\n<meta name=\"description\" content=\"Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Article, Chemistry - An Asian Journal called Sequential SNAr Reaction\/Suzuki-Miyaura Coupling\/C-H Direct Arylations Approach for the Rapid Synthesis of Tetraaryl-Substituted Pyrazoles, Author is Morita, Taiki; Kobayashi, Daisuke; Matsumura, Keisuke; Johmoto, Kohei; Uekusa, Hidehiro; Fuse, Shinichiro; Takahashi, Takashi, which mentions a compound: 52287-51-1, SMILESS is BrC1=CC=C2OCCOC2=C1, Molecular C8H7BrO2, Category: pyrazoles-derivatives.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=9684\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Now Is The Time For You To Know The Truth About 52287-51-1 | pyrazoles-derivatives\" \/>\n<meta property=\"og:description\" content=\"Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Article, Chemistry - An Asian Journal called Sequential SNAr Reaction\/Suzuki-Miyaura Coupling\/C-H Direct Arylations Approach for the Rapid Synthesis of Tetraaryl-Substituted Pyrazoles, Author is Morita, Taiki; Kobayashi, Daisuke; Matsumura, Keisuke; Johmoto, Kohei; Uekusa, Hidehiro; Fuse, Shinichiro; Takahashi, Takashi, which mentions a compound: 52287-51-1, SMILESS is BrC1=CC=C2OCCOC2=C1, Molecular C8H7BrO2, Category: pyrazoles-derivatives.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.pyrazoles-derivatives.com\/?p=9684\" \/>\n<meta property=\"og:site_name\" content=\"pyrazoles-derivatives\" \/>\n<meta property=\"article:published_time\" content=\"2022-04-17T23:58:40+00:00\" \/>\n<meta name=\"author\" content=\"Jessica.F\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jessica.F\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=9684\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=9684\",\"name\":\"Now Is The Time For You To Know The Truth About 52287-51-1 | pyrazoles-derivatives\",\"isPartOf\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\"},\"datePublished\":\"2022-04-17T23:58:40+00:00\",\"author\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\"},\"description\":\"Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Article, Chemistry - An Asian Journal called Sequential SNAr Reaction\/Suzuki-Miyaura Coupling\/C-H Direct Arylations Approach for the Rapid Synthesis of Tetraaryl-Substituted Pyrazoles, Author is Morita, Taiki; Kobayashi, Daisuke; Matsumura, Keisuke; Johmoto, Kohei; Uekusa, Hidehiro; Fuse, Shinichiro; Takahashi, Takashi, which mentions a compound: 52287-51-1, SMILESS is BrC1=CC=C2OCCOC2=C1, Molecular C8H7BrO2, Category: pyrazoles-derivatives.\",\"breadcrumb\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=9684#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.pyrazoles-derivatives.com\/?p=9684\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=9684#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"\u9996\u9875\",\"item\":\"https:\/\/www.pyrazoles-derivatives.com\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Now Is The Time For You To Know The Truth About 52287-51-1\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/\",\"name\":\"pyrazoles-derivatives\",\"description\":\"Several pyrazole derivatives possess important pharmacological activities and they have been proved useful materials in drug research. 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A Journal, Article, Chemistry - An Asian Journal called Sequential SNAr Reaction\/Suzuki-Miyaura Coupling\/C-H Direct Arylations Approach for the Rapid Synthesis of Tetraaryl-Substituted Pyrazoles, Author is Morita, Taiki; Kobayashi, Daisuke; Matsumura, Keisuke; Johmoto, Kohei; Uekusa, Hidehiro; Fuse, Shinichiro; Takahashi, Takashi, which mentions a compound: 52287-51-1, SMILESS is BrC1=CC=C2OCCOC2=C1, Molecular C8H7BrO2, Category: pyrazoles-derivatives.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.pyrazoles-derivatives.com\/?p=9684","og_locale":"en_US","og_type":"article","og_title":"Now Is The Time For You To Know The Truth About 52287-51-1 | pyrazoles-derivatives","og_description":"Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Article, Chemistry - An Asian Journal called Sequential SNAr Reaction\/Suzuki-Miyaura Coupling\/C-H Direct Arylations Approach for the Rapid Synthesis of Tetraaryl-Substituted Pyrazoles, Author is Morita, Taiki; Kobayashi, Daisuke; Matsumura, Keisuke; Johmoto, Kohei; Uekusa, Hidehiro; Fuse, Shinichiro; Takahashi, Takashi, which mentions a compound: 52287-51-1, SMILESS is BrC1=CC=C2OCCOC2=C1, Molecular C8H7BrO2, Category: pyrazoles-derivatives.","og_url":"https:\/\/www.pyrazoles-derivatives.com\/?p=9684","og_site_name":"pyrazoles-derivatives","article_published_time":"2022-04-17T23:58:40+00:00","author":"Jessica.F","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Jessica.F","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.pyrazoles-derivatives.com\/?p=9684","url":"https:\/\/www.pyrazoles-derivatives.com\/?p=9684","name":"Now Is The Time For You To Know The Truth About 52287-51-1 | pyrazoles-derivatives","isPartOf":{"@id":"https:\/\/www.pyrazoles-derivatives.com\/#website"},"datePublished":"2022-04-17T23:58:40+00:00","author":{"@id":"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1"},"description":"Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. 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