{"id":9641,"date":"2022-04-13T10:20:33","date_gmt":"2022-04-13T02:20:33","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=9641"},"modified":"2022-04-13T10:20:33","modified_gmt":"2022-04-13T02:20:33","slug":"discovery-of-17190-29-3-4","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=9641","title":{"rendered":"Discovery of 17190-29-3"},"content":{"rendered":"<p>The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 3-Hydroxy-3-phenylpropanenitrile( cas:17190-29-3 ) is researched.<a href=\"https:\/\/www.ambeed.com\/products\/17190-29-3.html\">Formula: C9H9NO<\/a>.Talwar, Dinesh; Wu, Xiaofeng; Saidi, Ourida; Salguero, Noemi Poyatos; Xiao, Jianliang published the article \u300aVersatile Iridicycle Catalysts for Highly Efficient and Chemoselective Transfer Hydrogenation of Carbonyl Compounds in Water\u300b about this compound( cas:17190-29-3 )  in Chemistry &#8211; A European Journal. Keywords: iridium transfer hydrogenation reduction carbonyl compound; carbonyl groups; cyclometalated complexes; iridium; transfer hydrogenation; water. Let&#8217;s learn more about this compound (cas:17190-29-3).<\/p>\n<p>Cyclometalated iridium complexes are shown to be highly efficient and chemoselective catalysts for the transfer hydrogenation of a wide range of carbonyl groups with formic acid in water. Examples include \u03b1-substituted ketones (\u03b1-ether, \u03b1-halo, \u03b1-hydroxy, \u03b1-amino, \u03b1-nitrile or \u03b1-ester), \u03b1-keto esters, \u03b2-keto esters and \u03b1,\u03b2-unsaturated aldehydes. The reduction was carried out at substrate\/catalyst ratios of up to 50 000 at pH 4.5 and required no organic solvent. The protocol provides a practical, easy and efficient way for the synthesis of \u03b2-functionalized secondary alcs., such as \u03b2-hydroxy-ethers, \u03b2-hydroxy-amines and \u03b2-hydroxyhalo compounds, which are valuable intermediates in pharmaceutical, fine chem., perfume and agrochem. synthesis. Under optimized conditions the synthesis of the target compounds was achieved using chloro[3-[1-[(4-methoxyphenyl)imino-\u03baN]ethyl]-2-naphthalenyl-\u03baC][(1,2,3,4,5-\u03b7)-1,2,3,4,5-pentamethyl-2,4-cyclopentadien-1-yl]iridium (naphthalene-imine complex) and chloro[2-[1-[(4-methoxyphenyl)imino-\u03baN]ethyl]-3-phenanthrenyl-\u03baC][(1,2,3,4,5-\u03b7)-1,2,3,4,5-pentamethyl-2,4-cyclopentadien-1-yl]iridium (phenanthrene-imine complex) as catalysts. The title compounds thus formed included \u03b1-[(4-chlorophenoxy)methyl]benzenemethanol \u03b1-[(3-pyridinyloxy)methyl]benzenemethanol, 1-phenoxy-2-propanol, 2-(ethoxy)cyclohexanol (ether-alc.), 1,4-anhydro-2,5-dideoxypentitol (carbohydrate sugar derivative), \u03b1-(chloromethyl)benzenemethanol, \u03b2-(hydroxy)benzenepropanenitrile, \u03b2-(hydroxy)thiophenepropanenitrile (thiophene derivative), \u03b2-(hydroxy)furanpropanenitrile (furan derivative), 1-phenyl-1,2-ethanediol benzoate and related substances, piperidine derivatives, morpholine derivatives, pyridine derivatives<\/p>\n<p>Although many compounds look similar to this compound(17190-29-3)<a href=\"https:\/\/www.ambeed.com\/products\/17190-29-3.html\">Formula: C9H9NO<\/a>, numerous studies have shown that this compound(SMILES:N#CCC(O)C1=CC=CC=C1), has unique advantages. If you want to know more about similar compounds, you can read my other articles.<\/p>\n<p>Reference:<br \/><a href=\"https:\/\/en.wikipedia.org\/wiki\/Pyrazole\">Pyrazole &#8211; Wikipedia<\/a>,<br \/><a href=\"https:\/\/www.sciencedirect.com\/topics\/chemistry\/pyrazoles\">Pyrazoles &#8211; an overview | ScienceDirect Topics<\/A><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Although many compounds look similar to this compound(17190-29-3)<a href=\"https:\/\/www.ambeed.com\/products\/17190-29-3.html\">Formula: C9H9NO<\/a>, numerous studies have shown that this compound(SMILES:N#CCC(O)C1=CC=CC=C1), has unique advantages. If you want to know more about similar compounds, you can read my other articles.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[723,131],"tags":[126],"class_list":["post-9641","post","type-post","status-publish","format-standard","hentry","category-17190-29-3","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Discovery of 17190-29-3 | pyrazoles-derivatives<\/title>\n<meta name=\"description\" content=\"The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 3-Hydroxy-3-phenylpropanenitrile( cas:17190-29-3 ) is researched.Formula: C9H9NO.Talwar, Dinesh; Wu, Xiaofeng; Saidi, Ourida; Salguero, Noemi Poyatos; Xiao, Jianliang published the article \u300aVersatile Iridicycle Catalysts for Highly Efficient and Chemoselective Transfer Hydrogenation of Carbonyl Compounds in Water\u300b about this compound( cas:17190-29-3 ) in Chemistry - A European Journal. Keywords: iridium transfer hydrogenation reduction carbonyl compound; carbonyl groups; cyclometalated complexes; iridium; transfer hydrogenation; water. 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Compound: 3-Hydroxy-3-phenylpropanenitrile( cas:17190-29-3 ) is researched.Formula: C9H9NO.Talwar, Dinesh; Wu, Xiaofeng; Saidi, Ourida; Salguero, Noemi Poyatos; Xiao, Jianliang published the article \u300aVersatile Iridicycle Catalysts for Highly Efficient and Chemoselective Transfer Hydrogenation of Carbonyl Compounds in Water\u300b about this compound( cas:17190-29-3 ) in Chemistry - A European Journal. Keywords: iridium transfer hydrogenation reduction carbonyl compound; carbonyl groups; cyclometalated complexes; iridium; transfer hydrogenation; water. 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Compound: 3-Hydroxy-3-phenylpropanenitrile( cas:17190-29-3 ) is researched.Formula: C9H9NO.Talwar, Dinesh; Wu, Xiaofeng; Saidi, Ourida; Salguero, Noemi Poyatos; Xiao, Jianliang published the article \u300aVersatile Iridicycle Catalysts for Highly Efficient and Chemoselective Transfer Hydrogenation of Carbonyl Compounds in Water\u300b about this compound( cas:17190-29-3 ) in Chemistry - A European Journal. Keywords: iridium transfer hydrogenation reduction carbonyl compound; carbonyl groups; cyclometalated complexes; iridium; transfer hydrogenation; water. 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Compound: 3-Hydroxy-3-phenylpropanenitrile( cas:17190-29-3 ) is researched.Formula: C9H9NO.Talwar, Dinesh; Wu, Xiaofeng; Saidi, Ourida; Salguero, Noemi Poyatos; Xiao, Jianliang published the article \u300aVersatile Iridicycle Catalysts for Highly Efficient and Chemoselective Transfer Hydrogenation of Carbonyl Compounds in Water\u300b about this compound( cas:17190-29-3 ) in Chemistry - A European Journal. Keywords: iridium transfer hydrogenation reduction carbonyl compound; carbonyl groups; cyclometalated complexes; iridium; transfer hydrogenation; water. 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Keywords: iridium transfer hydrogenation reduction carbonyl compound; carbonyl groups; cyclometalated complexes; iridium; transfer hydrogenation; water. Let's learn more about this compound (cas:17190-29-3).","og_url":"https:\/\/www.pyrazoles-derivatives.com\/?p=9641","og_site_name":"pyrazoles-derivatives","article_published_time":"2022-04-13T02:20:33+00:00","author":"Jessica.F","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Jessica.F","Est. reading time":"2 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.pyrazoles-derivatives.com\/?p=9641","url":"https:\/\/www.pyrazoles-derivatives.com\/?p=9641","name":"Discovery of 17190-29-3 | pyrazoles-derivatives","isPartOf":{"@id":"https:\/\/www.pyrazoles-derivatives.com\/#website"},"datePublished":"2022-04-13T02:20:33+00:00","author":{"@id":"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1"},"description":"The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 3-Hydroxy-3-phenylpropanenitrile( cas:17190-29-3 ) is researched.Formula: C9H9NO.Talwar, Dinesh; Wu, Xiaofeng; Saidi, Ourida; Salguero, Noemi Poyatos; Xiao, Jianliang published the article \u300aVersatile Iridicycle Catalysts for Highly Efficient and Chemoselective Transfer Hydrogenation of Carbonyl Compounds in Water\u300b about this compound( cas:17190-29-3 ) in Chemistry - A European Journal. Keywords: iridium transfer hydrogenation reduction carbonyl compound; carbonyl groups; cyclometalated complexes; iridium; transfer hydrogenation; water. 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