{"id":9569,"date":"2022-04-08T05:13:06","date_gmt":"2022-04-07T21:13:06","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=9569"},"modified":"2022-04-08T05:13:06","modified_gmt":"2022-04-07T21:13:06","slug":"continuously-updated-synthesis-method-about-1300746-79-5","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=9569","title":{"rendered":"Continuously updated synthesis method about 1300746-79-5"},"content":{"rendered":"<p>The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: (1,10-Phenanthroline)(trifluoromethyl)copper(I)( cas:1300746-79-5 ) is researched.<a href=\"https:\/\/www.ambeed.com\/products\/1300746-79-5.html\">Product Details of 1300746-79-5<\/a>.Dibrell, Sara E.; Maser, Michael R.; Reisman, Sarah E. published the article \u300aSeO2-Mediated Oxidative Transposition of Pauson-Khand Products\u300b about this compound( cas:1300746-79-5 )  in Journal of the American Chemical Society. Keywords: bicyclic cyclopentenone oxidative transposition selenium dioxide mediated. Let&#8217;s learn more about this compound (cas:1300746-79-5).<\/p>\n<p>Oxidative transpositions of bicyclic cyclopentenones I [R1 = Me, Ph, n-hexyl, 3-pyridyl, etc.; R2 = H, Me; R3 = H, Me, Ph; R32 = (CH2)5, CH2CH2NBocCH2CH2; X = O, NBoc, C(CO2Et)2, C(CO2i-Pr)2] mediated by selenium dioxide (SeO2) has been disclosed. Treatment of Pauson-Khand (PKR) reaction products I with SeO2 in the presence or absence of water furnished the corresponding di- and trioxidized cyclopentenones II and III [from I (R2 = H)], resp. Mechanistic investigations revealed multiple competing oxidation pathways that depend on substrate identity and water concentration Functionalization of the oxidized products via cross-coupling methods demonstrated their synthetic utility. These transformations allows rapid access to oxidatively transposed cyclopentenones from simple PKR products.<\/p>\n<p>I hope my short article helps more people learn about this compound((1,10-Phenanthroline)(trifluoromethyl)copper(I))<a href=\"https:\/\/www.ambeed.com\/products\/1300746-79-5.html\">Product Details of 1300746-79-5<\/a>. Apart from the compound(1300746-79-5), you can read my other articles to know other related compounds.<\/p>\n<p>Reference:<br \/><a href=\"https:\/\/en.wikipedia.org\/wiki\/Pyrazole\">Pyrazole &#8211; Wikipedia<\/a>,<br \/><a href=\"https:\/\/www.sciencedirect.com\/topics\/chemistry\/pyrazoles\">Pyrazoles &#8211; an overview | ScienceDirect Topics<\/A><\/p>\n","protected":false},"excerpt":{"rendered":"<p>I hope my short article helps more people learn about this compound((1,10-Phenanthroline)(trifluoromethyl)copper(I))<a href=\"https:\/\/www.ambeed.com\/products\/1300746-79-5.html\">Product Details of 1300746-79-5<\/a>. Apart from the compound(1300746-79-5), you can read my other articles to know other related compounds.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[726,131],"tags":[167],"class_list":["post-9569","post","type-post","status-publish","format-standard","hentry","category-1300746-79-5","category-pyrazoles-derivatives","tag-m-w300-400"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Continuously updated synthesis method about 1300746-79-5 | pyrazoles-derivatives<\/title>\n<meta name=\"description\" content=\"The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: (1,10-Phenanthroline)(trifluoromethyl)copper(I)( cas:1300746-79-5 ) is researched.Product Details of 1300746-79-5.Dibrell, Sara E.; Maser, Michael R.; Reisman, Sarah E. published the article \u300aSeO2-Mediated Oxidative Transposition of Pauson-Khand Products\u300b about this compound( cas:1300746-79-5 ) in Journal of the American Chemical Society. Keywords: bicyclic cyclopentenone oxidative transposition selenium dioxide mediated. Let&#039;s learn more about this compound (cas:1300746-79-5).\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=9569\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Continuously updated synthesis method about 1300746-79-5 | pyrazoles-derivatives\" \/>\n<meta property=\"og:description\" content=\"The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: (1,10-Phenanthroline)(trifluoromethyl)copper(I)( cas:1300746-79-5 ) is researched.Product Details of 1300746-79-5.Dibrell, Sara E.; Maser, Michael R.; Reisman, Sarah E. published the article \u300aSeO2-Mediated Oxidative Transposition of Pauson-Khand Products\u300b about this compound( cas:1300746-79-5 ) in Journal of the American Chemical Society. Keywords: bicyclic cyclopentenone oxidative transposition selenium dioxide mediated. 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Compound: (1,10-Phenanthroline)(trifluoromethyl)copper(I)( cas:1300746-79-5 ) is researched.Product Details of 1300746-79-5.Dibrell, Sara E.; Maser, Michael R.; Reisman, Sarah E. published the article \u300aSeO2-Mediated Oxidative Transposition of Pauson-Khand Products\u300b about this compound( cas:1300746-79-5 ) in Journal of the American Chemical Society. Keywords: bicyclic cyclopentenone oxidative transposition selenium dioxide mediated. 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Pyrazole derivatives play an important role in antitumor agents.\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"http:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\",\"name\":\"Jessica.F\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/cn.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/cn.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"caption\":\"Jessica.F\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Continuously updated synthesis method about 1300746-79-5 | pyrazoles-derivatives","description":"The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: (1,10-Phenanthroline)(trifluoromethyl)copper(I)( cas:1300746-79-5 ) is researched.Product Details of 1300746-79-5.Dibrell, Sara E.; Maser, Michael R.; Reisman, Sarah E. published the article \u300aSeO2-Mediated Oxidative Transposition of Pauson-Khand Products\u300b about this compound( cas:1300746-79-5 ) in Journal of the American Chemical Society. Keywords: bicyclic cyclopentenone oxidative transposition selenium dioxide mediated. Let's learn more about this compound (cas:1300746-79-5).","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.pyrazoles-derivatives.com\/?p=9569","og_locale":"en_US","og_type":"article","og_title":"Continuously updated synthesis method about 1300746-79-5 | pyrazoles-derivatives","og_description":"The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: (1,10-Phenanthroline)(trifluoromethyl)copper(I)( cas:1300746-79-5 ) is researched.Product Details of 1300746-79-5.Dibrell, Sara E.; Maser, Michael R.; Reisman, Sarah E. published the article \u300aSeO2-Mediated Oxidative Transposition of Pauson-Khand Products\u300b about this compound( cas:1300746-79-5 ) in Journal of the American Chemical Society. Keywords: bicyclic cyclopentenone oxidative transposition selenium dioxide mediated. Let's learn more about this compound (cas:1300746-79-5).","og_url":"https:\/\/www.pyrazoles-derivatives.com\/?p=9569","og_site_name":"pyrazoles-derivatives","article_published_time":"2022-04-07T21:13:06+00:00","author":"Jessica.F","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Jessica.F","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.pyrazoles-derivatives.com\/?p=9569","url":"https:\/\/www.pyrazoles-derivatives.com\/?p=9569","name":"Continuously updated synthesis method about 1300746-79-5 | pyrazoles-derivatives","isPartOf":{"@id":"http:\/\/www.pyrazoles-derivatives.com\/#website"},"datePublished":"2022-04-07T21:13:06+00:00","author":{"@id":"http:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1"},"description":"The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: (1,10-Phenanthroline)(trifluoromethyl)copper(I)( cas:1300746-79-5 ) is researched.Product Details of 1300746-79-5.Dibrell, Sara E.; Maser, Michael R.; Reisman, Sarah E. published the article \u300aSeO2-Mediated Oxidative Transposition of Pauson-Khand Products\u300b about this compound( cas:1300746-79-5 ) in Journal of the American Chemical Society. Keywords: bicyclic cyclopentenone oxidative transposition selenium dioxide mediated. 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