{"id":943,"date":"2020-11-04T10:51:24","date_gmt":"2020-11-04T02:51:24","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=943"},"modified":"2020-11-04T10:51:24","modified_gmt":"2020-11-04T02:51:24","slug":"introduction-of-a-new-synthetic-route-about-pyrazole-3-carboxaldehyde","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=943","title":{"rendered":"Introduction of a new synthetic route about Pyrazole-3-carboxaldehyde"},"content":{"rendered":"

3920-50-1<\/a>, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 3920-50-1 name is Pyrazole-3-carboxaldehyde, This compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.<\/p>\n

3.9 mg of 1H-pyrazole-3-carboxaldehyde was added to a dimethylformamide (0.5 ml) solution of 15 mg of 4-(2-fluoro-phenoxy)-5-(6-methanesulfonyl-pyridin-3-yloxy)-benzene-1,2-diamine obtained in Example 200, and the reaction liquid was stirred at 90\u00a1\u00e3C for 30 minutes. The solvent was evaporated away under reduced pressure, and the resulting residue was purified through partitioning thin-layer chromatography (Kieselgel.(TM). 60F254, Art 5744 (by Merck), chloroform\/methanol = 9\/1) to obtain the entitled compound as a white solid. 1HNMR(CDCl3)delta: 3.20(3H,s), 6.94-6.99(1H,m), 7.01-7.15(4H,m), 7.25-7.65(2H,m), 7.31(1H,dd,J=8.9,2.7Hz), 7.66(1H,d,J=2.3Hz), 7.98(1H,d,J=8.9Hz), 8.40(1H,d,J=2.7Hz) ESI-MS(m\/e):466[M+H]<\/p>\n

At the same time, in my other blogs, there are other synthetic methods of this type of compound, Pyrazole-3-carboxaldehyde, and friends who are interested can also refer to it.<\/p>\n","protected":false},"excerpt":{"rendered":"

At the same time, in my other blogs, there are other synthetic methods of this type of compound, Pyrazole-3-carboxaldehyde, and friends who are interested can also refer to it.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[156,131],"tags":[145],"class_list":["post-943","post","type-post","status-publish","format-standard","hentry","category-3920-50-1","category-pyrazoles-derivatives","tag-m-w0-100"],"yoast_head":"\nIntroduction of a new synthetic route about Pyrazole-3-carboxaldehyde<\/title>\n<meta name=\"description\" content=\"3920-50-1, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 3920-50-1 name is Pyrazole-3-carboxaldehyde, This compound is widely used in many fields, so it is necessary to find a new synthetic route. 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