{"id":9427,"date":"2022-03-30T09:50:14","date_gmt":"2022-03-30T01:50:14","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=9427"},"modified":"2022-03-30T09:50:14","modified_gmt":"2022-03-30T01:50:14","slug":"a-new-application-about-7153-13-1","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=9427","title":{"rendered":"A new application about 7153-13-1"},"content":{"rendered":"<p>The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 2-Amino-4,6-dichloro-5-methylpyrimidine(SMILESS: CC1=C(N=C(N)N=C1Cl)Cl,cas:7153-13-1) is researched.<a href=\"https:\/\/www.ambeed.com\/products\/7153-13-1.html\">Electric Literature of C17H18Cl2N2<\/a>. The article \u300aCombining Quantum Mechanical Ligand Conformation Analysis and Protein Modeling to Elucidate GPCR-Ligand Binding Modes\u300b in relation to this compound, is published in ChemMedChem. Let&#8217;s take a look at the latest research on this compound (cas:7153-13-1).<\/p>\n<p>2-Aminopyrimidine ligands with flexible and rigid side chains was synthesized to investigate the role of ligand conformation in H4R ligand binding. The ligand binding conformations and orientations in the H4R binding pocket was elucidated. The combined ligand- and protein-ligand modeling method can be used as a general approach to investigate the binding modes of flexible side chains of ligands with other protein targets.<\/p>\n<p>If you want to learn more about this compound(2-Amino-4,6-dichloro-5-methylpyrimidine)<a href=\"https:\/\/www.ambeed.com\/products\/7153-13-1.html\">Related Products of 7153-13-1<\/a>, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(7153-13-1).<\/p>\n<p>Reference:<br \/><a href=\"https:\/\/en.wikipedia.org\/wiki\/Pyrazole\">Pyrazole &#8211; Wikipedia<\/a>,<br \/><a href=\"https:\/\/www.sciencedirect.com\/topics\/chemistry\/pyrazoles\">Pyrazoles &#8211; an overview | ScienceDirect Topics<\/A><\/p>\n","protected":false},"excerpt":{"rendered":"<p>If you want to learn more about this compound(2-Amino-4,6-dichloro-5-methylpyrimidine)<a href=\"https:\/\/www.ambeed.com\/products\/7153-13-1.html\">Related Products of 7153-13-1<\/a>, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(7153-13-1).<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[729,131],"tags":[126],"class_list":["post-9427","post","type-post","status-publish","format-standard","hentry","category-7153-13-1","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>A new application about 7153-13-1 | pyrazoles-derivatives<\/title>\n<meta name=\"description\" content=\"The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 2-Amino-4,6-dichloro-5-methylpyrimidine(SMILESS: CC1=C(N=C(N)N=C1Cl)Cl,cas:7153-13-1) is researched.Electric Literature of C17H18Cl2N2. The article \u300aCombining Quantum Mechanical Ligand Conformation Analysis and Protein Modeling to Elucidate GPCR-Ligand Binding Modes\u300b in relation to this compound, is published in ChemMedChem. Let&#039;s take a look at the latest research on this compound (cas:7153-13-1).\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=9427\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"A new application about 7153-13-1 | pyrazoles-derivatives\" \/>\n<meta property=\"og:description\" content=\"The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 2-Amino-4,6-dichloro-5-methylpyrimidine(SMILESS: CC1=C(N=C(N)N=C1Cl)Cl,cas:7153-13-1) is researched.Electric Literature of C17H18Cl2N2. The article \u300aCombining Quantum Mechanical Ligand Conformation Analysis and Protein Modeling to Elucidate GPCR-Ligand Binding Modes\u300b in relation to this compound, is published in ChemMedChem. Let&#039;s take a look at the latest research on this compound (cas:7153-13-1).\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.pyrazoles-derivatives.com\/?p=9427\" \/>\n<meta property=\"og:site_name\" content=\"pyrazoles-derivatives\" \/>\n<meta property=\"article:published_time\" content=\"2022-03-30T01:50:14+00:00\" \/>\n<meta name=\"author\" content=\"Jessica.F\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jessica.F\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=9427\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=9427\",\"name\":\"A new application about 7153-13-1 | pyrazoles-derivatives\",\"isPartOf\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\"},\"datePublished\":\"2022-03-30T01:50:14+00:00\",\"author\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\"},\"description\":\"The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 2-Amino-4,6-dichloro-5-methylpyrimidine(SMILESS: CC1=C(N=C(N)N=C1Cl)Cl,cas:7153-13-1) is researched.Electric Literature of C17H18Cl2N2. The article \u300aCombining Quantum Mechanical Ligand Conformation Analysis and Protein Modeling to Elucidate GPCR-Ligand Binding Modes\u300b in relation to this compound, is published in ChemMedChem. 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Pyrazole derivatives play an important role in antitumor agents.\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\",\"name\":\"Jessica.F\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"caption\":\"Jessica.F\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"A new application about 7153-13-1 | pyrazoles-derivatives","description":"The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 2-Amino-4,6-dichloro-5-methylpyrimidine(SMILESS: CC1=C(N=C(N)N=C1Cl)Cl,cas:7153-13-1) is researched.Electric Literature of C17H18Cl2N2. The article \u300aCombining Quantum Mechanical Ligand Conformation Analysis and Protein Modeling to Elucidate GPCR-Ligand Binding Modes\u300b in relation to this compound, is published in ChemMedChem. Let's take a look at the latest research on this compound (cas:7153-13-1).","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.pyrazoles-derivatives.com\/?p=9427","og_locale":"en_US","og_type":"article","og_title":"A new application about 7153-13-1 | pyrazoles-derivatives","og_description":"The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. 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Compound: 2-Amino-4,6-dichloro-5-methylpyrimidine(SMILESS: CC1=C(N=C(N)N=C1Cl)Cl,cas:7153-13-1) is researched.Electric Literature of C17H18Cl2N2. The article \u300aCombining Quantum Mechanical Ligand Conformation Analysis and Protein Modeling to Elucidate GPCR-Ligand Binding Modes\u300b in relation to this compound, is published in ChemMedChem. 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