{"id":9417,"date":"2022-03-30T09:50:14","date_gmt":"2022-03-30T01:50:14","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=9417"},"modified":"2022-03-30T09:50:14","modified_gmt":"2022-03-30T01:50:14","slug":"the-influence-of-catalyst-in-reaction-17190-29-3","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=9417","title":{"rendered":"The influence of catalyst in reaction 17190-29-3"},"content":{"rendered":"<p>Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: 3-Hydroxy-3-phenylpropanenitrile, is researched, Molecular C9H9NO, CAS is 17190-29-3, about Iridium-catalyzed efficient reduction of ketones in water with formic acid as a hydride donor at low catalyst loading.<a href=\"https:\/\/www.ambeed.com\/products\/17190-29-3.html\">Application In Synthesis of  3-Hydroxy-3-phenylpropanenitrile<\/a>.<\/p>\n<p>A highly efficient and chemoselective transfer hydrogenation of ketones in water has been successfully achieved with our newly developed catalyst. Simple ketones, as well as \u03b1- or \u03b2-functionalized ketones, are readily reduced. Formic acid is used as a traceless hydride source. At very low catalyst loading (S\/C = 10 000 in most cases; S\/C = 50 000 or 100 000 in some cases), the iridium catalyst is impressively efficient at reducing ketones in good to excellent yields. The TOF value can be as high as up to 26 000 mol mol-1 h-1. A variety of functional groups are well tolerated, for example, heteroaryl, aryloxy, alkyloxy, halogen, cyano, nitro, ester, especially acidic methylene, phenol and carboxylic acid groups.<\/p>\n<p>If you want to learn more about this compound(3-Hydroxy-3-phenylpropanenitrile)<a href=\"https:\/\/www.ambeed.com\/products\/17190-29-3.html\">Application In Synthesis of  3-Hydroxy-3-phenylpropanenitrile<\/a>, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(17190-29-3).<\/p>\n<p>Reference:<br \/><a href=\"https:\/\/en.wikipedia.org\/wiki\/Pyrazole\">Pyrazole &#8211; Wikipedia<\/a>,<br \/><a href=\"https:\/\/www.sciencedirect.com\/topics\/chemistry\/pyrazoles\">Pyrazoles &#8211; an overview | ScienceDirect Topics<\/A><\/p>\n","protected":false},"excerpt":{"rendered":"<p>If you want to learn more about this compound(3-Hydroxy-3-phenylpropanenitrile)<a href=\"https:\/\/www.ambeed.com\/products\/17190-29-3.html\">Application In Synthesis of  3-Hydroxy-3-phenylpropanenitrile<\/a>, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(17190-29-3).<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[723,131],"tags":[126],"class_list":["post-9417","post","type-post","status-publish","format-standard","hentry","category-17190-29-3","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>The influence of catalyst in reaction 17190-29-3 | pyrazoles-derivatives<\/title>\n<meta name=\"description\" content=\"Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: 3-Hydroxy-3-phenylpropanenitrile, is researched, Molecular C9H9NO, CAS is 17190-29-3, about Iridium-catalyzed efficient reduction of ketones in water with formic acid as a hydride donor at low catalyst loading.Application In Synthesis of 3-Hydroxy-3-phenylpropanenitrile.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=9417\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"The influence of catalyst in reaction 17190-29-3 | pyrazoles-derivatives\" \/>\n<meta property=\"og:description\" content=\"Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: 3-Hydroxy-3-phenylpropanenitrile, is researched, Molecular C9H9NO, CAS is 17190-29-3, about Iridium-catalyzed efficient reduction of ketones in water with formic acid as a hydride donor at low catalyst loading.Application In Synthesis of 3-Hydroxy-3-phenylpropanenitrile.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.pyrazoles-derivatives.com\/?p=9417\" \/>\n<meta property=\"og:site_name\" content=\"pyrazoles-derivatives\" \/>\n<meta property=\"article:published_time\" content=\"2022-03-30T01:50:14+00:00\" \/>\n<meta name=\"author\" content=\"Jessica.F\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jessica.F\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=9417\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=9417\",\"name\":\"The influence of catalyst in reaction 17190-29-3 | pyrazoles-derivatives\",\"isPartOf\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\"},\"datePublished\":\"2022-03-30T01:50:14+00:00\",\"author\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\"},\"description\":\"Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: 3-Hydroxy-3-phenylpropanenitrile, is researched, Molecular C9H9NO, CAS is 17190-29-3, about Iridium-catalyzed efficient reduction of ketones in water with formic acid as a hydride donor at low catalyst loading.Application In Synthesis of 3-Hydroxy-3-phenylpropanenitrile.\",\"breadcrumb\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=9417#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.pyrazoles-derivatives.com\/?p=9417\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=9417#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"\u9996\u9875\",\"item\":\"https:\/\/www.pyrazoles-derivatives.com\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"The influence of catalyst in reaction 17190-29-3\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/\",\"name\":\"pyrazoles-derivatives\",\"description\":\"Several pyrazole derivatives possess important pharmacological activities and they have been proved useful materials in drug research. Pyrazole derivatives play an important role in antitumor agents.\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\",\"name\":\"Jessica.F\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/cn.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/cn.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"caption\":\"Jessica.F\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"The influence of catalyst in reaction 17190-29-3 | pyrazoles-derivatives","description":"Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: 3-Hydroxy-3-phenylpropanenitrile, is researched, Molecular C9H9NO, CAS is 17190-29-3, about Iridium-catalyzed efficient reduction of ketones in water with formic acid as a hydride donor at low catalyst loading.Application In Synthesis of 3-Hydroxy-3-phenylpropanenitrile.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.pyrazoles-derivatives.com\/?p=9417","og_locale":"en_US","og_type":"article","og_title":"The influence of catalyst in reaction 17190-29-3 | pyrazoles-derivatives","og_description":"Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: 3-Hydroxy-3-phenylpropanenitrile, is researched, Molecular C9H9NO, CAS is 17190-29-3, about Iridium-catalyzed efficient reduction of ketones in water with formic acid as a hydride donor at low catalyst loading.Application In Synthesis of 3-Hydroxy-3-phenylpropanenitrile.","og_url":"https:\/\/www.pyrazoles-derivatives.com\/?p=9417","og_site_name":"pyrazoles-derivatives","article_published_time":"2022-03-30T01:50:14+00:00","author":"Jessica.F","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Jessica.F","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.pyrazoles-derivatives.com\/?p=9417","url":"https:\/\/www.pyrazoles-derivatives.com\/?p=9417","name":"The influence of catalyst in reaction 17190-29-3 | pyrazoles-derivatives","isPartOf":{"@id":"https:\/\/www.pyrazoles-derivatives.com\/#website"},"datePublished":"2022-03-30T01:50:14+00:00","author":{"@id":"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1"},"description":"Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: 3-Hydroxy-3-phenylpropanenitrile, is researched, Molecular C9H9NO, CAS is 17190-29-3, about Iridium-catalyzed efficient reduction of ketones in water with formic acid as a hydride donor at low catalyst loading.Application In Synthesis of 3-Hydroxy-3-phenylpropanenitrile.","breadcrumb":{"@id":"https:\/\/www.pyrazoles-derivatives.com\/?p=9417#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.pyrazoles-derivatives.com\/?p=9417"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.pyrazoles-derivatives.com\/?p=9417#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"\u9996\u9875","item":"https:\/\/www.pyrazoles-derivatives.com\/"},{"@type":"ListItem","position":2,"name":"The influence of catalyst in reaction 17190-29-3"}]},{"@type":"WebSite","@id":"https:\/\/www.pyrazoles-derivatives.com\/#website","url":"https:\/\/www.pyrazoles-derivatives.com\/","name":"pyrazoles-derivatives","description":"Several pyrazole derivatives possess important pharmacological activities and they have been proved useful materials in drug research. 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