{"id":906,"date":"2020-10-30T10:37:01","date_gmt":"2020-10-30T02:37:01","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=906"},"modified":"2020-10-30T10:37:01","modified_gmt":"2020-10-30T02:37:01","slug":"new-downstream-synthetic-route-of-3-methyl-1-phenyl-1h-pyrazole","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=906","title":{"rendered":"New downstream synthetic route of 3-Methyl-1-phenyl-1H-pyrazole"},"content":{"rendered":"

Adding a certain compound to certain chemical reactions, such as: 1128-54-7, name is 3-Methyl-1-phenyl-1H-pyrazole, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 1128-54-7, 1128-54-7<\/a><\/p>\n

To the reaction flaskwas added 3-methyl-1-phenyl -1H- pyrazole (0.50 g, 0.003 mol), 5 ml of toluene,heated to 70 C, the reaction solution was added N- bromosuccinimide (0.40 g,0.003 mol), azobisisobutyronitrile (catalytic amount), plus Was completed, thereaction solution was warmed to reflux, the reaction was refluxed for 1 hour.After the reaction was cooled to below 30 C, the reaction solution was pouredinto 50 ml Liters of water with 3 \u00a1\u00c1 50 ml of ethyl acetate and extracted, theresultant organic phase was washed with saturated aqueous sodium bicarbonate(50 ml), saturated After aqueous sodium chloride solution (50 ml), dried overanhydrous magnesium sulfate, and concentrated under reduced pressure, theresidue was purified by column chromatography (Eluent: ethyl acetate: petroleumether = 1: 100) to give 0.40 g of 3-bromo-1-phenyl -1H- pyrazole as a yellowoil, yield 56 %.<\/p>\n

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 3-Methyl-1-phenyl-1H-pyrazole, other downstream synthetic routes, hurry up and to see.<\/p>\n","protected":false},"excerpt":{"rendered":"

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 3-Methyl-1-phenyl-1H-pyrazole, other downstream synthetic routes, hurry up and to see.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[182,131],"tags":[126],"class_list":["post-906","post","type-post","status-publish","format-standard","hentry","category-1128-54-7","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nNew downstream synthetic route of 3-Methyl-1-phenyl-1H-pyrazole<\/title>\n<meta name=\"description\" content=\"Adding a certain compound to certain chemical reactions, such as: 1128-54-7, name is 3-Methyl-1-phenyl-1H-pyrazole, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 1128-54-7, 1128-54-7\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"http:\/\/www.pyrazoles-derivatives.com\/?p=906\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"New downstream synthetic route of 3-Methyl-1-phenyl-1H-pyrazole\" \/>\n<meta property=\"og:description\" content=\"Adding a certain compound to certain chemical reactions, such as: 1128-54-7, name is 3-Methyl-1-phenyl-1H-pyrazole, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. 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Pyrazole derivatives play an important role in antitumor agents.\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\",\"name\":\"Jessica.F\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"caption\":\"Jessica.F\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"New downstream synthetic route of 3-Methyl-1-phenyl-1H-pyrazole","description":"Adding a certain compound to certain chemical reactions, such as: 1128-54-7, name is 3-Methyl-1-phenyl-1H-pyrazole, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. 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