{"id":6824,"date":"2021-10-14T02:25:16","date_gmt":"2021-10-13T18:25:16","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=6824"},"modified":"2021-10-14T02:25:16","modified_gmt":"2021-10-13T18:25:16","slug":"something-interesting-about-35-dimethyl-1h-pyrazole-2","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=6824","title":{"rendered":"Something interesting about 3,5-Dimethyl-1H-pyrazole"},"content":{"rendered":"<p>Glukhacheva, VS; Il&#8217;yasov, SG; Kazantsev, IV; Shestakova, EO; Il&#8217;yasov, DS; Eltsov, IV; Nefedov, AA; Gatilov, YV in [Glukhacheva, Vera S.; Il&#8217;yasov, Sergey G.; Kazantsev, Igor, V; Shestakova, Elena O.; Il&#8217;yasov, Dmitri S.] Russian Acad Sci IPCET SB RAS, Inst Problems Chem &#038; Energet Technol, Siberian Branch, Biisk 659322, Russia; [Eltsov, Ilia, V; Nefedov, Andrey A.] Novosibirsk State Univ, Novosibirsk 630090, Russia; [Nefedov, Andrey A.; Gatilov, Yuri, V] Russian Acad Sci NIOCh SB RAS, Vorozhtsov Novosibirsk Inst Organ Chem, Siberian Branch, Novosibirsk 630090, Russia published New Reaction Products of Acetylacetone with Semicarbazide Derivatives in 2021.0, Cited 40.0. <a href=\"https:\/\/www.ambeed.com\/products\/67-51-6.html\">Recommanded Product: 67-51-6<\/a>. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6.<\/p>\n<p>A new approach is suggested herein for the synthesis of pyrazole derivatives by reacting 4-nitrosemicarbazide with acetylacetone. Additional studies were done on the reaction of acetylacetone with semicarbazide and its derivatives (4-aminosemicarbazide, methylsemicarbazide, and dimethylsemicarbazide). The study on the reaction with acetylacetone resulted in monocyclic 3,5-dimethyl-N-nitropyrazole-1-carboxamide, monocyclic 5-hydroxy-3,5-dimethyl-2-pyrazoline, and bicyclic bis(3,5-dimethylpyrazole-1-carbonyl)hydrazine, and conditions for the formation of acetone semicarbazone were identified. The structures of the resultant compounds were validated by physicochemical analytical methods, including X-ray diffraction. The computer-aided screening in the PASS prediction software discovered a high biological activity of the newly obtained compounds.<\/p>\n<p><a href=\"https:\/\/www.ambeed.com\/products\/67-51-6.html\">Recommanded Product: 67-51-6<\/a>. About 3,5-Dimethyl-1H-pyrazole, If you have any questions, you can contact Glukhacheva, VS; Il&#8217;yasov, SG; Kazantsev, IV; Shestakova, EO; Il&#8217;yasov, DS; Eltsov, IV; Nefedov, AA; Gatilov, YV or concate me.<\/p>\n<p>Reference:<br \/><a href=\"https:\/\/en.wikipedia.org\/wiki\/Pyrazole\">Pyrazole &#8211; Wikipedia<\/a>,<br \/>,<a href=\"https:\/\/www.sciencedirect.com\/topics\/chemistry\/pyrazoles\">Pyrazoles &#8211; an overview | ScienceDirect Topics<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p><a href=\"https:\/\/www.ambeed.com\/products\/67-51-6.html\">Recommanded Product: 67-51-6<\/a>. About 3,5-Dimethyl-1H-pyrazole, If you have any questions, you can contact Glukhacheva, VS; Il&#8217;yasov, SG; Kazantsev, IV; Shestakova, EO; Il&#8217;yasov, DS; Eltsov, IV; Nefedov, AA; Gatilov, YV or concate me.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[249,131],"tags":[145],"class_list":["post-6824","post","type-post","status-publish","format-standard","hentry","category-67-51-6","category-pyrazoles-derivatives","tag-m-w0-100"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Something interesting about 3,5-Dimethyl-1H-pyrazole | pyrazoles-derivatives<\/title>\n<meta name=\"description\" content=\"Glukhacheva, VS; Il&#039;yasov, SG; Kazantsev, IV; Shestakova, EO; Il&#039;yasov, DS; Eltsov, IV; Nefedov, AA; Gatilov, YV in [Glukhacheva, Vera S.; Il&#039;yasov, Sergey G.; Kazantsev, Igor, V; Shestakova, Elena O.; Il&#039;yasov, Dmitri S.] Russian Acad Sci IPCET SB RAS, Inst Problems Chem &amp; Energet Technol, Siberian Branch, Biisk 659322, Russia; [Eltsov, Ilia, V; Nefedov, Andrey A.] Novosibirsk State Univ, Novosibirsk 630090, Russia; [Nefedov, Andrey A.; Gatilov, Yuri, V] Russian Acad Sci NIOCh SB RAS, Vorozhtsov Novosibirsk Inst Organ Chem, Siberian Branch, Novosibirsk 630090, Russia published New Reaction Products of Acetylacetone with Semicarbazide Derivatives in 2021.0, Cited 40.0. Recommanded Product: 67-51-6. The Name is 3,5-Dimethyl-1H-pyrazole. 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Recommanded Product: 67-51-6. The Name is 3,5-Dimethyl-1H-pyrazole. 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Recommanded Product: 67-51-6. The Name is 3,5-Dimethyl-1H-pyrazole. 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Recommanded Product: 67-51-6. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6.","breadcrumb":{"@id":"https:\/\/www.pyrazoles-derivatives.com\/?p=6824#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.pyrazoles-derivatives.com\/?p=6824"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.pyrazoles-derivatives.com\/?p=6824#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"\u9996\u9875","item":"https:\/\/www.pyrazoles-derivatives.com\/"},{"@type":"ListItem","position":2,"name":"Something interesting about 3,5-Dimethyl-1H-pyrazole"}]},{"@type":"WebSite","@id":"https:\/\/www.pyrazoles-derivatives.com\/#website","url":"https:\/\/www.pyrazoles-derivatives.com\/","name":"pyrazoles-derivatives","description":"Several pyrazole derivatives possess important pharmacological activities and they have been proved useful materials in drug research. 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