{"id":6544,"date":"2021-09-29T03:39:24","date_gmt":"2021-09-28T19:39:24","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=6544"},"modified":"2021-09-29T03:39:24","modified_gmt":"2021-09-28T19:39:24","slug":"29-sep-news-new-learning-discoveries-about-16617-46-2","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=6544","title":{"rendered":"29-Sep News New learning discoveries about 16617-46-2"},"content":{"rendered":"

Synthetic Route of 16617-46-2<\/a>, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 16617-46-2, name is 3-Amino-1H-pyrazole-4-carbonitrile belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below.<\/p>\n

General procedure: A solution of aldehyde (2\u00a0mmol), 3-aminopyrazole (1\u00a0mmol), and p-toluenesulfonic acid catalyst (20\u00a0mol\u00a0percent) in MeCN (5\u00a0mL) was magnetically stirred for 24\u00a0h in room temperature. Next TsCH2NC (1\u00a0mmol) was added and the reaction mixture was stirred for 24\u00a0h in room temperature. After completion of the reaction, which was followed by TLC EtOAc\/petroleum ether 4:1, the reaction mixture was filtered, and the precipitate washed with methanol. Finally pure solid product was obtained by column chromatography.<\/p>\n

The synthetic route of 3-Amino-1H-pyrazole-4-carbonitrile has been constantly updated, and we look forward to future research findings.<\/p>\n

Reference:
Article; Rahmati, Abbas; Eskandari-Vashareh, Miranda; Alizadeh-Kouzehrash, Meysam; Tetrahedron; vol. 69; 21; (2013); p. 4199 – 4204;<\/a>,
Pyrazole – Wikipedia<\/a>,
Pyrazoles – an overview | ScienceDirect Topics<\/p>\n","protected":false},"excerpt":{"rendered":"

The synthetic route of 3-Amino-1H-pyrazole-4-carbonitrile has been constantly updated, and we look forward to future research findings.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[193,131],"tags":[126],"class_list":["post-6544","post","type-post","status-publish","format-standard","hentry","category-16617-46-2","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nNew learning discoveries about<\/title>\n<meta name=\"description\" content=\"Synthetic Route of 16617-46-2, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 16617-46-2, name is 3-Amino-1H-pyrazole-4-carbonitrile belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=6544\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"New learning discoveries about\" \/>\n<meta property=\"og:description\" content=\"Synthetic Route of 16617-46-2, In the next few decades, the world population will flourish. 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