{"id":6526,"date":"2021-09-28T03:21:40","date_gmt":"2021-09-27T19:21:40","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=6526"},"modified":"2021-09-28T03:21:40","modified_gmt":"2021-09-27T19:21:40","slug":"28-sep-2021-news-a-new-synthetic-route-of-41680-34-6","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=6526","title":{"rendered":"28-Sep-2021 News A new synthetic route of 41680-34-6"},"content":{"rendered":"<p>Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 41680-34-6, name is 3-Amino-1H-pyrazole-4-carboxylic acid, A new synthetic method of this compound is introduced below., <a href=\"https:\/\/www.ambeed.com\/products\/41680-34-6.html\">Application In Synthesis of  3-Amino-1H-pyrazole-4-carboxylic acid<\/a><\/p>\n<p>A solution of 5-amino-1H-pyrazole-4-carboxylic acid (2000 mg, 15.74 mmol) and (E)-3- (dimethylamino)-2-methylacrylaldehyde (1780 mg, 15.74 mmol) in acetic acid (3 mL) and ethanol (1 mL) was heated at 70 oC for 1h. The resulting mixture was cooled to room temperature and the solid was collected by filtration, washed with water and dried in vacuum to afford 6-methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid (1610 mg, 58%) as a white solid. MS (ESI): m\/z = 178.1 [M+1]+.<\/p>\n<p>The synthetic route of 41680-34-6 has been constantly updated, and we look forward to future research findings.<\/p>\n<p>Reference:<br \/><a href=\"http:\/\/v3.espacenet.com\/textdoc?DB=EPODOC&#038;IDX=WO2017108723&#038;F=0\">Patent; F. HOFFMANN-LA ROCHE AG; GENENTECH, INC.; BRYAN, Marian, C.; GOBBI, Alberto; KIEFER, James, Richard, Jr.; KOLESNIKOV, Aleksandr; OLIVERO, Alan, G.; DROBNICK, Joy; LIANG, Jun; RAJAPAKSA, Naomi; (846 pag.)WO2017\/108723; (2017); A2;<\/a>,<br \/><a href=\"https:\/\/en.wikipedia.org\/wiki\/Pyrazole\">Pyrazole &#8211; Wikipedia<\/a>,<br \/><a href=\"https:\/\/www.sciencedirect.com\/topics\/chemistry\/pyrazoles\">Pyrazoles &#8211; an overview | ScienceDirect Topics<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The synthetic route of 41680-34-6 has been constantly updated, and we look forward to future research findings.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[208,131],"tags":[126],"class_list":["post-6526","post","type-post","status-publish","format-standard","hentry","category-41680-34-6","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>A new synthetic route of<\/title>\n<meta name=\"description\" content=\"Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. 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Generally, it requires fewer steps, and cheap raw materials. 41680-34-6, name is 3-Amino-1H-pyrazole-4-carboxylic acid, A new synthetic method of this compound is introduced below., Application In Synthesis of 3-Amino-1H-pyrazole-4-carboxylic acid\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.pyrazoles-derivatives.com\/?p=6526\" \/>\n<meta property=\"og:site_name\" content=\"pyrazoles-derivatives\" \/>\n<meta property=\"article:published_time\" content=\"2021-09-27T19:21:40+00:00\" \/>\n<meta name=\"author\" content=\"Jessica.F\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jessica.F\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=6526\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=6526\",\"name\":\"A new synthetic route of\",\"isPartOf\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\"},\"datePublished\":\"2021-09-27T19:21:40+00:00\",\"author\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\"},\"description\":\"Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. 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Generally, it requires fewer steps, and cheap raw materials. 41680-34-6, name is 3-Amino-1H-pyrazole-4-carboxylic acid, A new synthetic method of this compound is introduced below., Application In Synthesis of 3-Amino-1H-pyrazole-4-carboxylic acid","og_url":"https:\/\/www.pyrazoles-derivatives.com\/?p=6526","og_site_name":"pyrazoles-derivatives","article_published_time":"2021-09-27T19:21:40+00:00","author":"Jessica.F","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Jessica.F","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.pyrazoles-derivatives.com\/?p=6526","url":"https:\/\/www.pyrazoles-derivatives.com\/?p=6526","name":"A new synthetic route of","isPartOf":{"@id":"https:\/\/www.pyrazoles-derivatives.com\/#website"},"datePublished":"2021-09-27T19:21:40+00:00","author":{"@id":"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1"},"description":"Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. 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