{"id":6475,"date":"2021-09-24T03:23:06","date_gmt":"2021-09-23T19:23:06","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=6475"},"modified":"2021-09-24T03:23:06","modified_gmt":"2021-09-23T19:23:06","slug":"sep-21-news-a-new-synthetic-route-of-1280210-79-8","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=6475","title":{"rendered":"Sep-21 News A new synthetic route of 1280210-79-8"},"content":{"rendered":"

In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 1280210-79-8, name is tert-Butyl 4,6-dihydropyrrolo[3,4-c]pyrazole-5(2H)-carboxylate belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below. HPLC of Formula: C10H15N3O2<\/a><\/p>\n

2D (3.5 g, 16.7 mmol) was dissolved in tetrahydrofuran (35 mL)Cooled to 0 C,60% sodium hydride (1.0 g, 25.4 mmol) was added,After reaction for 30 minutes, methylsulfonyl chloride (2.9 g, 25.4 mmol) was added and reacted for 1 hour.The reaction mixture was quenched with water (10 mL) and extracted with ethyl acetate (50 mL x 2). The organic layers were combined and the organic layer was dried over anhydrous sodium sulfate and concentrated. The residue was purified by silica gel column chromatography (petroleum ether \/ Ethyl acetate (v \/ v) = 1: 1) to give 2E as a white solid (2.1 g, yield 44%).<\/p>\n

The synthetic route of 1280210-79-8 has been constantly updated, and we look forward to future research findings.<\/p>\n

Reference:
Patent; SICHUAN HAISCO PHARMACEUTICAL CO., LTD; ZHANG, CHEN; FAN, JIANG; LEI, MING; WEI, YONG-GANG; (61 pag.)TW2017\/8223; (2017); A;<\/a>,
Pyrazole – Wikipedia<\/a>,
Pyrazoles – an overview | ScienceDirect Topics<\/p>\n","protected":false},"excerpt":{"rendered":"

The synthetic route of 1280210-79-8 has been constantly updated, and we look forward to future research findings.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[222,131],"tags":[127],"class_list":["post-6475","post","type-post","status-publish","format-standard","hentry","category-1280210-79-8","category-pyrazoles-derivatives","tag-m-w200-300"],"yoast_head":"\nA new synthetic route of<\/title>\n<meta name=\"description\" content=\"In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 1280210-79-8, name is tert-Butyl 4,6-dihydropyrrolo[3,4-c]pyrazole-5(2H)-carboxylate belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below. 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