{"id":6062,"date":"2021-08-27T03:37:33","date_gmt":"2021-08-26T19:37:33","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=6062"},"modified":"2021-08-27T03:37:33","modified_gmt":"2021-08-26T19:37:33","slug":"the-important-role-of-c3h4n2-3","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=6062","title":{"rendered":"The important role of C3H4N2"},"content":{"rendered":"

Adding a certain compound to certain chemical reactions, such as: 288-13-1, name is 1H-Pyrazole, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 288-13-1, Quality Control of 1H-Pyrazole<\/a><\/p>\n

General procedure: A mixture of the appropriate N-nucleophile (2 mmol), 4-bromonitrobenzene(2 mmol), t-ButOK or KOH (in the case of 1g, 1h)(2.2 mmol) in dimethyl sulfoxide (2.5 mL) was stirred at 60 C for 5 h(8 h in the case of 1b). After cooling and addition of water (60 mL),either a solid precipitated which was filtered, washed with water andrecrystallised from an appropriate solvent to give the product, or asuspension was generated which was extracted with ethyl acetate(3 \u00d7 30 mL), dried over Na2SO4, concentrated under reduced pressureand recrystallised from an appropriate solvent to give the desiredproduct<\/p>\n

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it.<\/p>\n

Reference:
Article; Ghasemi, Zarrin; Shahrak, Nasim Shahi; Roomi, Behzad Jalali; Zakeri, Ziba; Journal of Chemical Research; vol. 39; 2; (2015); p. 73 – 75;<\/a>,
Pyrazole – Wikipedia<\/a>,
Pyrazoles – an overview | ScienceDirect Topics<\/p>\n","protected":false},"excerpt":{"rendered":"

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[149,131],"tags":[145],"class_list":["post-6062","post","type-post","status-publish","format-standard","hentry","category-288-13-1","category-pyrazoles-derivatives","tag-m-w0-100"],"yoast_head":"\nThe important role of<\/title>\n<meta name=\"description\" content=\"Adding a certain compound to certain chemical reactions, such as: 288-13-1, name is 1H-Pyrazole, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. 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