{"id":6045,"date":"2021-08-26T03:15:58","date_gmt":"2021-08-25T19:15:58","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=6045"},"modified":"2021-08-26T03:15:58","modified_gmt":"2021-08-25T19:15:58","slug":"the-important-role-of-c5h6n2o2-2","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=6045","title":{"rendered":"The important role of C5H6N2O2"},"content":{"rendered":"

Adding a certain compound to certain chemical reactions, such as: 402-61-9, name is 5-Methyl-1H-pyrazole-3-carboxylic acid, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 402-61-9, Formula: C5H6N2O2<\/a><\/p>\n

Step C: N-rr4i?)-6-r4-Chlorophenvn-7-(2.4-dichlorophenvn-2.2-dimethyl-3.4-dihvdro-2\/\/- pyrano [2,3-frlrhoyridin-4-yll -5 -methyl- 1.H-pyrazole-3 -carboxamide; . A mixture of the product of Step B (300 mg, 0.69 mmol), S-methylpyrazole-S-carboxylic acid (105 mg, 0.83 mmol), PyBOP (540 mg, 1.04 mmol), and NEt3 (0.19 mL, 1.38 mmol) in 20 mL Of CH2Cl2 was stirred at rt. After 16 h, the reaction mixture was diluted with Et2O (50 mL), washed with saturated aq NaHCO3 (3×50 mL) and brine (3×50 mL). The organic layer was separated, dried over MgSO4 and concentrated. Chromatography on a Biotage 40+S cartridge using 1 : 1 v\/v EtOAc\/Hexanes as the eluant afforded the title compound: 1H NMR delta 1.44 (s, 3H), 1.51 (s, 3H), 1.94 (t, J= 12.5, IH), 2.26-2.30 (m, 4H), 5.62 (m, IH), 6.58 (s, IH), 6.96 (d, J= 8.5, 2H), 7.12-7.29 (m, 5H), 7.69 (s, IH).<\/p>\n

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 5-Methyl-1H-pyrazole-3-carboxylic acid, other downstream synthetic routes, hurry up and to see.<\/p>\n

Reference:
Patent; MERCK & CO., INC.; WO2008\/94476; (2008); A1;<\/a>,
Pyrazole – Wikipedia<\/a>,
Pyrazoles – an overview | ScienceDirect Topics<\/p>\n","protected":false},"excerpt":{"rendered":"

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 5-Methyl-1H-pyrazole-3-carboxylic acid, other downstream synthetic routes, hurry up and to see.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[159,131],"tags":[126],"class_list":["post-6045","post","type-post","status-publish","format-standard","hentry","category-402-61-9","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nThe important role of<\/title>\n<meta name=\"description\" content=\"Adding a certain compound to certain chemical reactions, such as: 402-61-9, name is 5-Methyl-1H-pyrazole-3-carboxylic acid, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 402-61-9, Formula: C5H6N2O2\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=6045\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"The important role of\" \/>\n<meta property=\"og:description\" content=\"Adding a certain compound to certain chemical reactions, such as: 402-61-9, name is 5-Methyl-1H-pyrazole-3-carboxylic acid, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. 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Pyrazole derivatives play an important role in antitumor agents.\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\",\"name\":\"Jessica.F\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/weavatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/weavatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"caption\":\"Jessica.F\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"The important role of","description":"Adding a certain compound to certain chemical reactions, such as: 402-61-9, name is 5-Methyl-1H-pyrazole-3-carboxylic acid, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. 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