{"id":5917,"date":"2021-08-18T03:28:48","date_gmt":"2021-08-17T19:28:48","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=5917"},"modified":"2021-08-18T03:28:48","modified_gmt":"2021-08-17T19:28:48","slug":"application-of-c12h12n2o2-2","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=5917","title":{"rendered":"Application of C12H12N2O2"},"content":{"rendered":"

Adding a certain compound to certain chemical reactions, such as: 13599-12-7, name is Ethyl 3-phenyl-1H-pyrazole-5-carboxylate, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 13599-12-7, category: pyrazoles-derivatives<\/a><\/p>\n

General procedure: A mixture of ethyl 3-aryl-1H-pyrazole-5-carboxylate 1 (2 mmol), N-aralkyl -2-chloroacetamide 7 (3 mmol), anhydrous potassium carbonate (4 mmol) and dry acetonitrile (60 ml) was refluxed for 1-5 h, after which the mixture was cooled to room temperature and filtered. The filtrate was condensed under reduced pressure. The crude product was purified by chromatographer on silica gel using PE\/EtOAc (3:1) as an eluent to afford the desired compounds 5.<\/p>\n

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it.<\/p>\n

Reference:
Article; Lv, Hong-Shui; Kong, Xiang-Qian; Ming, Qian-Qian; Jin, Xing; Miao, Jun-Ying; Zhao, Bao-Xiang; Bioorganic and Medicinal Chemistry Letters; vol. 22; 2; (2012); p. 844 – 849;<\/a>,
Pyrazole – Wikipedia<\/a>,
Pyrazoles – an overview | ScienceDirect Topics<\/p>\n","protected":false},"excerpt":{"rendered":"

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[282,131],"tags":[127],"class_list":["post-5917","post","type-post","status-publish","format-standard","hentry","category-13599-12-7","category-pyrazoles-derivatives","tag-m-w200-300"],"yoast_head":"\nApplication of<\/title>\n<meta name=\"description\" content=\"Adding a certain compound to certain chemical reactions, such as: 13599-12-7, name is Ethyl 3-phenyl-1H-pyrazole-5-carboxylate, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. 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