{"id":5853,"date":"2021-08-13T03:58:56","date_gmt":"2021-08-12T19:58:56","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=5853"},"modified":"2021-08-13T03:58:56","modified_gmt":"2021-08-12T19:58:56","slug":"simple-exploration-of-c11h11brn2","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=5853","title":{"rendered":"Simple exploration of C11H11BrN2"},"content":{"rendered":"

Adding a certain compound to certain chemical reactions, such as: 294877-29-5, name is 1-(3-Bromophenyl)-3,5-dimethyl-1H-pyrazole, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 294877-29-5, HPLC of Formula: C11H11BrN2<\/a><\/p>\n

In another step, 2-[3-(3,5-Dimethylpyrazol-1-yl)-phenoxy]-N-(tetrahydropyranyl)carbazole was synthesized. To a 100 mL sealed tube was added with N-tetrahydropyranyl-2-hydroxycarbazole (880 mg, 3.0 mmol), N-(3-Bromophenyl)-3,5-dimethylpyrazole (826 mg, 3.30 mmol), Cesium carbonate (2.9 g, 3 mmol), copper(I) iodide (57 mg, 0.3 mmol), N,N-dimethylglycine (93 mg, 0.9 mmol) and 1,4-dioxane (8 mL) in glove box, and the mixture was stirred at 90 C. for 3 days. After cooling to rt, the mixture was treated with water (75 mL) and ethyl acetate (40 mL), and the water phase was extracted with ethyl acetate (3\u00d730 mL). The organic extracted phase was combined, washed with brine (3\u00d730 mL), dried with magnesium sulfate and concentrated. The resulting crude product was purified with an silica gel chromatography with hexane\/ethyl acetate=3:1 as eluent to give an white colloidal solid. (1.12 g, 79% yield).<\/p>\n

At the same time, in my other blogs, there are other synthetic methods of this type of compound, 1-(3-Bromophenyl)-3,5-dimethyl-1H-pyrazole, and friends who are interested can also refer to it.<\/p>\n

Reference:
Patent; Li, Jian; Turner, Eric; Hang, Xiaochun; US2012\/215001; (2012); A1;<\/a>,
Pyrazole – Wikipedia<\/a>,
Pyrazoles – an overview | ScienceDirect Topics<\/p>\n","protected":false},"excerpt":{"rendered":"

At the same time, in my other blogs, there are other synthetic methods of this type of compound, 1-(3-Bromophenyl)-3,5-dimethyl-1H-pyrazole, and friends who are interested can also refer to it.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[599,131],"tags":[127],"class_list":["post-5853","post","type-post","status-publish","format-standard","hentry","category-294877-29-5","category-pyrazoles-derivatives","tag-m-w200-300"],"yoast_head":"\nSimple exploration of<\/title>\n<meta name=\"description\" content=\"Adding a certain compound to certain chemical reactions, such as: 294877-29-5, name is 1-(3-Bromophenyl)-3,5-dimethyl-1H-pyrazole, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 294877-29-5, HPLC of Formula: C11H11BrN2\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=5853\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Simple exploration of\" \/>\n<meta property=\"og:description\" content=\"Adding a certain compound to certain chemical reactions, such as: 294877-29-5, name is 1-(3-Bromophenyl)-3,5-dimethyl-1H-pyrazole, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. 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