{"id":5834,"date":"2021-08-12T03:29:24","date_gmt":"2021-08-11T19:29:24","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=5834"},"modified":"2021-08-12T03:29:24","modified_gmt":"2021-08-11T19:29:24","slug":"the-important-role-of-c10h11n3","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=5834","title":{"rendered":"The important role of C10H11N3"},"content":{"rendered":"

Related Products of 368870-03-5<\/a>, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 368870-03-5, name is (4-(1H-Pyrazol-1-yl)phenyl)methanamine belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below.<\/p>\n

4-(Pyrazol-1-yl)benzylamine (12.2 g, 0.07 mol) was dissolved in 50 mL of 2-methoxyethanol (75 mL) and 3-isopropyl-pyrimidine-5,7-dithiol (2) (13.3 g, 0.059 mol) was added under an atmosphere of nitrogen. The reaction mixture was heated at 120 C for 12 hours. The reaction product crystallized upon cooling to 10-15 C and was filtered off. After washing with 2-methoxyethanol, then THF, and drying in vacuo at 75 C, 13.7 g of product are obtained in 62% yield. The analytical sample was recrystallized from DMS0\/H20, dried at 75 C under vacuum; m.p. 268-270 C (decomposition), UV (nm): 268 l, 288 l, 300 l, 336 l?. MS ESI+ 366.1 (M+H)+, ESI- 364.1 (M-H) . NMR (500 MHz; DMSO-d6): 1.23 (d, \/ = 7.03 Hz, 6H, -CH(C\/\/3)2); 3.44 (bs, 1H, -C\/\/(CH3)2); 4.75 (d, J = 6.11 Hz, 2H, -NH-G-); 6.50-6.51 (m, 1H, HAT); 7.46 (d, \/ = 7.95 Hz, 2H, HAT); 7.71 (d, \/ = 1.53 Hz, 1H, HAT); 7.79 (d, J = 8.25 Hz, 2H, HAT) ; 8.45 (d, J = 2.45 Hz, 1H, HAT) ; 9.17 (bs, 1H, -NH-); l2.23(bs, 1H, -NH); 13.74 (bs, 1H, -SH). 13C (125 MHz; DMSO-d6): 21.8; 42.4; 107.7; 118.3; 127.6; 128.7; 138.7; 140.8. Anal. (CI8H19N7S) C, H, N, S.<\/p>\n

The synthetic route of (4-(1H-Pyrazol-1-yl)phenyl)methanamine has been constantly updated, and we look forward to future research findings.<\/p>\n

Reference:
Patent; UNIVERZITA PALACKEHO V OLOMOUCI; USTAV EXPERIMENTALNI BOTANIKY AV CR, V.V.I.; HAVLICEK, Libor; STURC, Antonin; REZNICKOVA, Eva; JORDA, Radek; KRYSTOF, Vladimir; STRNAD, Miroslav; (66 pag.)WO2019\/149295; (2019); A1;<\/a>,
Pyrazole – Wikipedia<\/a>,
Pyrazoles – an overview | ScienceDirect Topics<\/p>\n","protected":false},"excerpt":{"rendered":"

The synthetic route of (4-(1H-Pyrazol-1-yl)phenyl)methanamine has been constantly updated, and we look forward to future research findings.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[322,131],"tags":[126],"class_list":["post-5834","post","type-post","status-publish","format-standard","hentry","category-368870-03-5","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nThe important role of<\/title>\n<meta name=\"description\" content=\"Related Products of 368870-03-5, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 368870-03-5, name is (4-(1H-Pyrazol-1-yl)phenyl)methanamine belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=5834\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"The important role of\" \/>\n<meta property=\"og:description\" content=\"Related Products of 368870-03-5, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 368870-03-5, name is (4-(1H-Pyrazol-1-yl)phenyl)methanamine belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.pyrazoles-derivatives.com\/?p=5834\" \/>\n<meta property=\"og:site_name\" content=\"pyrazoles-derivatives\" \/>\n<meta property=\"article:published_time\" content=\"2021-08-11T19:29:24+00:00\" \/>\n<meta name=\"author\" content=\"Jessica.F\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jessica.F\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=5834\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=5834\",\"name\":\"The important role of\",\"isPartOf\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\"},\"datePublished\":\"2021-08-11T19:29:24+00:00\",\"author\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\"},\"description\":\"Related Products of 368870-03-5, In the next few decades, the world population will flourish. 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