{"id":5803,"date":"2021-08-11T05:23:12","date_gmt":"2021-08-10T21:23:12","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=5803"},"modified":"2021-08-11T05:23:12","modified_gmt":"2021-08-10T21:23:12","slug":"discovery-of-304903-10-4-2","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=5803","title":{"rendered":"Discovery of 304903-10-4"},"content":{"rendered":"

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 304903-10-4, name is 1-Ethyl-1H-pyrazole-4-carbaldehyde, A new synthetic method of this compound is introduced below., Quality Control of 1-Ethyl-1H-pyrazole-4-carbaldehyde<\/a><\/p>\n

in room temperature, Mix 1-ethyl-1H-pyrazole-4-carbaldehyde (12.4 g, 0.1 mol), sodium bromate (30.2 g, 0.2 mol) and 200 g of acetic acid, and add 50 g of ammonia containing 25% molecular weight of ammonia. And 600 ml of water, heated to 90 C, the reaction is exothermic, maintain the reaction temperature of 100 C, reflux reaction for 1 hour until 1-ethyl-1H-pyrazole-4-carbaldehyde complete reaction, the reaction solution is cooled to room temperature, poured into The mixture was diluted with ice water, neutralized until the reaction solution was neutral, extracted with ethyl acetate, dried, concentrated, and then distilled under reduced pressure and recrystallized to give 11.1 g of product, yield 92%, purity over 99%.<\/p>\n

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.<\/p>\n

Reference:
Patent; Changsha Luxing Biological Technology Co., Ltd.; Tan Yongjun; (14 pag.)CN108707113; (2018); A;<\/a>,
Pyrazole – Wikipedia<\/a>,
Pyrazoles – an overview | ScienceDirect Topics<\/p>\n","protected":false},"excerpt":{"rendered":"

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[262,131],"tags":[126],"class_list":["post-5803","post","type-post","status-publish","format-standard","hentry","category-304903-10-4","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nDiscovery of<\/title>\n<meta name=\"description\" content=\"Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. 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