{"id":5747,"date":"2021-08-06T03:22:28","date_gmt":"2021-08-05T19:22:28","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=5747"},"modified":"2021-08-06T03:22:28","modified_gmt":"2021-08-05T19:22:28","slug":"brief-introduction-of-13-dimethyl-1h-pyrazol-5-ol","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=5747","title":{"rendered":"Brief introduction of 1,3-Dimethyl-1H-pyrazol-5-ol"},"content":{"rendered":"

Adding a certain compound to certain chemical reactions, such as: 5203-77-0, name is 1,3-Dimethyl-1H-pyrazol-5-ol, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 5203-77-0, Recommanded Product: 1,3-Dimethyl-1H-pyrazol-5-ol<\/a><\/p>\n

Step 7: Synthesis of 1,3-dimethyl-5-(2-methyl-3-(methylthio)-4-(pentafluoroethyl)benzoyloxy)pyrazole360 mg (1.20 mmol) of 2-methyl-3-(methylthio)-4-(pentafluoroethyl)benzoic acid were introduced into 20 ml of dry dichloromethane and admixed in succession with 198 mg (1.56 mmol) of oxalyl dichloride and also with two drops of N,N-dimethyl-formamide. After the end of evolution of gas, the mixture was heated under reflux for 10 minutes. When a check on the reaction by thin-layer chromatography had indicated complete conversion, the contents were freed from the solvent, and the residue was then taken up in 20 ml of dry dichloromethane. The mixture was admixed with 161 mg (1.44 mmol) of 5-hydroxy-1,3-dimethylpyrazole, and then 243 mg (2.40 mmol) of triethylamine were added dropwise. The contents were stirred at RT for 16 hours. For working up, 3 ml of 1M hydrochloric acid were added, and, following phase separation, the organic phase was freed from the solvent. The residue, finally, was purified by chromatography, giving 410 mg of clean product.<\/p>\n

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1,3-Dimethyl-1H-pyrazol-5-ol, other downstream synthetic routes, hurry up and to see.<\/p>\n

Reference:
Patent; BAYER CROPSCIENCE AG; US2012\/21903; (2012); A1;<\/a>,
Pyrazole – Wikipedia<\/a>,
Pyrazoles – an overview | ScienceDirect Topics<\/p>\n","protected":false},"excerpt":{"rendered":"

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1,3-Dimethyl-1H-pyrazol-5-ol, other downstream synthetic routes, hurry up and to see.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[253,131],"tags":[126],"class_list":["post-5747","post","type-post","status-publish","format-standard","hentry","category-5203-77-0","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nBrief introduction of<\/title>\n<meta name=\"description\" content=\"Adding a certain compound to certain chemical reactions, such as: 5203-77-0, name is 1,3-Dimethyl-1H-pyrazol-5-ol, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. 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