{"id":5745,"date":"2021-08-06T03:22:28","date_gmt":"2021-08-05T19:22:28","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=5745"},"modified":"2021-08-06T03:22:28","modified_gmt":"2021-08-05T19:22:28","slug":"brief-introduction-of-c22h17brn2","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=5745","title":{"rendered":"Brief introduction of C22H17BrN2"},"content":{"rendered":"

Adding a certain compound to certain chemical reactions, such as: 95162-14-4, name is 4-Bromo-1-tritylpyrazole, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 95162-14-4, Computed Properties of C22H17BrN2<\/a><\/p>\n

A mixture of 4-bromo-4-trityl-1H-pyrazole (4.8 g, 12.3 mmol) described in Manufacturing Example 32-1-1, bis(pinacolate)diboran (5.0 g, 19.7 mmol), potassium acetate (3.62 g, 36.9 mmoL), 1,1′ bis(diphenylphosphino)ferrocene dichloropalladium(II) (450 mg, 0.62 mmol) and dimethyl sulfoxide (50 mL) was stirred under argon atmosphere for 17 hours and 10 minutes at 80 C. The reaction solution was allowed to room temperature, and partitioned into water and ethyl acetate. The organic layer was concentrated under a reduced pressure. The residue was purified by silica gel chromatography (heptane:ethyl acetate=4:1). Heptane was added to the solids obtained by concentrating the eluate under a reduced pressure, which were then irradiated by ultrasonic wave and filtered to obtain the title compound (1.51 g, 28.0%). 1H-NMR Spectrum (CDCl3) delta (ppm): 1.30 (12H, s), 7.10-7.16 (6H, m), 7.26-7.31 (9H, m), 7.75 (1H, s), 7.94 (1H, s).<\/p>\n

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 4-Bromo-1-tritylpyrazole, other downstream synthetic routes, hurry up and to see.<\/p>\n

Reference:
Patent; Eisai R&D Management Co., Ltd.; US2007\/105904; (2007); A1;<\/a>,
Pyrazole – Wikipedia<\/a>,
Pyrazoles – an overview | ScienceDirect Topics<\/p>\n","protected":false},"excerpt":{"rendered":"

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 4-Bromo-1-tritylpyrazole, other downstream synthetic routes, hurry up and to see.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[252,131],"tags":[167],"class_list":["post-5745","post","type-post","status-publish","format-standard","hentry","category-95162-14-4","category-pyrazoles-derivatives","tag-m-w300-400"],"yoast_head":"\nBrief introduction of<\/title>\n<meta name=\"description\" content=\"Adding a certain compound to certain chemical reactions, such as: 95162-14-4, name is 4-Bromo-1-tritylpyrazole, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. 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