{"id":5717,"date":"2021-08-05T03:16:12","date_gmt":"2021-08-04T19:16:12","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=5717"},"modified":"2021-08-05T03:16:12","modified_gmt":"2021-08-04T19:16:12","slug":"simple-exploration-of-tert-butyl-tert-butoxycarbonylamino1h-pyrazol-1-ylmethylenecarbamate-3","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=5717","title":{"rendered":"Simple exploration of tert-Butyl (((tert-butoxycarbonyl)amino)(1H-pyrazol-1-yl)methylene)carbamate"},"content":{"rendered":"<p>152120-54-2, name is tert-Butyl (((tert-butoxycarbonyl)amino)(1H-pyrazol-1-yl)methylene)carbamate, belongs to pyrazoles-derivatives compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. <a href=\"https:\/\/www.ambeed.com\/products\/152120-54-2.html\">category: pyrazoles-derivatives<\/a><\/p>\n<p>General procedure: A mixture of 62a (30 mg), N,N&#8217;-bis(tert-butoxycarbonyl)-1H-pyrazole-1-carboxamidine (11) (48 mg), diisopropylethylamine (0.02 mL) and CH2Cl2 (0.6 mL) was stirred at room temperature for 12 h under a nitrogen atmosphere. The solvent was removed in vacuo. The residue was purified by flash column chromatography over silica gel with CHCl3\/MeOH (10:1) as an eluent to give 63a (47 mg, 100%) as a colorless powder.<\/p>\n<p>The synthetic route of 152120-54-2 has been constantly updated, and we look forward to future research findings.<\/p>\n<p>Reference:<br \/><a href=\"https:\/\/doi.org\/10.1016\/j.bmc.2013.02.048\">Article; Inoue, Takayuki; Morita, Masataka; Tojo, Takashi; Nagashima, Akira; Moritomo, Ayako; Imai, Keisuke; Miyake, Hiroshi; Bioorganic and Medicinal Chemistry; vol. 21; 9; (2013); p. 2478 &#8211; 2494;<\/a>,<br \/><a href=\"https:\/\/en.wikipedia.org\/wiki\/Pyrazole\">Pyrazole &#8211; Wikipedia<\/a>,<br \/><a href=\"https:\/\/www.sciencedirect.com\/topics\/chemistry\/pyrazoles\">Pyrazoles &#8211; an overview | ScienceDirect Topics<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The synthetic route of 152120-54-2 has been constantly updated, and we look forward to future research findings.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[254,131],"tags":[167],"class_list":["post-5717","post","type-post","status-publish","format-standard","hentry","category-152120-54-2","category-pyrazoles-derivatives","tag-m-w300-400"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Simple exploration of<\/title>\n<meta name=\"description\" content=\"152120-54-2, name is tert-Butyl (((tert-butoxycarbonyl)amino)(1H-pyrazol-1-yl)methylene)carbamate, belongs to pyrazoles-derivatives compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. 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