{"id":5616,"date":"2021-07-30T06:06:27","date_gmt":"2021-07-29T22:06:27","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=5616"},"modified":"2021-07-30T06:06:27","modified_gmt":"2021-07-29T22:06:27","slug":"the-important-role-of-27006-76-4-2","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=5616","title":{"rendered":"The important role of 27006-76-4"},"content":{"rendered":"

Reference of 27006-76-4<\/a>, The chemical industry reduces the impact on the environment during synthesis 27006-76-4, name is 5-Chloro-1,3-dimethyl-1H-pyrazole-4-carboxaldehyde, I believe this compound will play a more active role in future production and life.<\/p>\n

General procedure: To a well stirred solution of substituted phenol (30 mmol) in DMF or DMSO (30 mL), KOH wasadded (40 mmol) at room temperature. The resulting mixture was heated to 40 C for 2-4 h, and thencompound 1 (20 mmol) was added thereto. The reaction solution was heated to 105 C for 8-24 h.After being cooled to room temperature, the mixture was poured into water and extracted with ethylacetate (3 50 mL). The combined extracts were dried over anhydrous magnesium sulfate, filtered,and evaporated to afford intermediate 2, with yields ranging from 52% to 76% [25].<\/p>\n

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 5-Chloro-1,3-dimethyl-1H-pyrazole-4-carboxaldehyde, other downstream synthetic routes, hurry up and to see.<\/p>\n

Reference:
Article; Dai, Hong; Yao, Wei; Fang, Yuan; Sun, Siyu; Shi, Yujun; Chen, Jia; Jiang, Guoqing; Shi, Jian; Molecules; vol. 22; 12; (2017);<\/a>,
Pyrazole – Wikipedia<\/a>,
Pyrazoles – an overview | ScienceDirect Topics<\/p>\n","protected":false},"excerpt":{"rendered":"

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 5-Chloro-1,3-dimethyl-1H-pyrazole-4-carboxaldehyde, other downstream synthetic routes, hurry up and to see.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[285,131],"tags":[126],"class_list":["post-5616","post","type-post","status-publish","format-standard","hentry","category-27006-76-4","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nThe important role of<\/title>\n<meta name=\"description\" content=\"Reference of 27006-76-4, The chemical industry reduces the impact on the environment during synthesis 27006-76-4, name is 5-Chloro-1,3-dimethyl-1H-pyrazole-4-carboxaldehyde, I believe this compound will play a more active role in future production and life.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=5616\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"The important role of\" \/>\n<meta property=\"og:description\" content=\"Reference of 27006-76-4, The chemical industry reduces the impact on the environment during synthesis 27006-76-4, name is 5-Chloro-1,3-dimethyl-1H-pyrazole-4-carboxaldehyde, I believe this compound will play a more active role in future production and life.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.pyrazoles-derivatives.com\/?p=5616\" \/>\n<meta property=\"og:site_name\" content=\"pyrazoles-derivatives\" \/>\n<meta property=\"article:published_time\" content=\"2021-07-29T22:06:27+00:00\" \/>\n<meta name=\"author\" content=\"Jessica.F\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jessica.F\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=5616\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=5616\",\"name\":\"The important role of\",\"isPartOf\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\"},\"datePublished\":\"2021-07-29T22:06:27+00:00\",\"author\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\"},\"description\":\"Reference of 27006-76-4, The chemical industry reduces the impact on the environment during synthesis 27006-76-4, name is 5-Chloro-1,3-dimethyl-1H-pyrazole-4-carboxaldehyde, I believe this compound will play a more active role in future production and life.\",\"breadcrumb\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=5616#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.pyrazoles-derivatives.com\/?p=5616\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=5616#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"\u9996\u9875\",\"item\":\"https:\/\/www.pyrazoles-derivatives.com\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"The important role of 27006-76-4\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/\",\"name\":\"pyrazoles-derivatives\",\"description\":\"Several pyrazole derivatives possess important pharmacological activities and they have been proved useful materials in drug research. 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