{"id":5603,"date":"2021-07-29T08:16:22","date_gmt":"2021-07-29T00:16:22","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=5603"},"modified":"2021-07-29T08:16:22","modified_gmt":"2021-07-29T00:16:22","slug":"some-scientific-research-about-313735-62-5","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=5603","title":{"rendered":"Some scientific research about 313735-62-5"},"content":{"rendered":"

Application of 313735-62-5<\/a>, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 313735-62-5, name is 4-Bromo-1-isopropylpyrazole, This compound has unique chemical properties. The synthetic route is as follows.<\/p>\n

To a solution of 4-bromo-l- (propan-2-yl)-lH-pyrazole (2 g, 10.58 mmol, 1.00 equiv) in Et20 (20 mL) maintained under nitrogen at -78 C was added dropwise a 2.5 M n-butyllithium solution (4.6 mL) in hexane. The reaction mixture was stirred at -78 C for 1 h. Sulfur dioxide gas was then bubbled in for 30 min. The reaction mixture was stirred at -78 C for 30 min and then warmed to rt. The solid was collected by filtration, washed with Et20 and dried in a vacuum to give 0.9 g (47%) of the title compound as a white solid. LCMS (Method G, ESI): RT =1.03 min, m\/z = 191.0.<\/p>\n

The chemical industry reduces the impact on the environment during synthesis 4-Bromo-1-isopropylpyrazole. I believe this compound will play a more active role in future production and life.<\/p>\n

Reference:
Patent; GENENTECH, INC.; FORMA TM, LLC; BAIR, Kenneth W.; BAUMEISTER, Timm R.; DRAGOVICH, Peter; ZAK, Mark; ZHAO, Guiling; ZHENG, Xiaozhang; WO2014\/74715; (2014); A1;<\/a>,
Pyrazole – Wikipedia<\/a>,
Pyrazoles – an overview | ScienceDirect Topics<\/p>\n","protected":false},"excerpt":{"rendered":"

The chemical industry reduces the impact on the environment during synthesis 4-Bromo-1-isopropylpyrazole. I believe this compound will play a more active role in future production and life.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[296,131],"tags":[126],"class_list":["post-5603","post","type-post","status-publish","format-standard","hentry","category-313735-62-5","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nSome scientific research about<\/title>\n<meta name=\"description\" content=\"Application of 313735-62-5, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 313735-62-5, name is 4-Bromo-1-isopropylpyrazole, This compound has unique chemical properties. 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