{"id":5497,"date":"2021-07-22T03:44:45","date_gmt":"2021-07-21T19:44:45","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=5497"},"modified":"2021-07-22T03:44:45","modified_gmt":"2021-07-21T19:44:45","slug":"new-learning-discoveries-about-181585-93-3","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=5497","title":{"rendered":"New learning discoveries about 181585-93-3"},"content":{"rendered":"

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 181585-93-3, name is Methyl 5-nitro-1H-pyrazole-3-carboxylate, A new synthetic method of this compound is introduced below., name: Methyl 5-nitro-1H-pyrazole-3-carboxylate<\/a><\/p>\n

2-tert-Butoxycarbonylmethyl-5-nitro-2H-pyrazole-3-carboxylic acid methyl ester: To a stirring mixture of delta-nitro^H-pyrazole-S-carboxylic acid methyl ester ( 3.5 gm, 20.5 mmol) dissolved in 150 ml of acetone was added cesium carbonate ( 8.01 gm, 24.6 mmol) followed by the addition of tert-butyl bromoacetate ( 3.61 ml). After 5 hours the solids were filtered and the mixture chromatographed on silica gel using 10% ethyl acetate\/hexanes as the eluent to obtain 4.16 gm of pure title product. ESI M+1= 286.<\/p>\n

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.<\/p>\n

Reference:
Patent; SCHERING CORPORATION; WO2006\/50034; (2006); A1;<\/a>,
Pyrazole – Wikipedia<\/a>,
Pyrazoles – an overview | ScienceDirect Topics<\/p>\n","protected":false},"excerpt":{"rendered":"

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[425,131],"tags":[126],"class_list":["post-5497","post","type-post","status-publish","format-standard","hentry","category-181585-93-3","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nNew learning discoveries about<\/title>\n<meta name=\"description\" content=\"Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 181585-93-3, name is Methyl 5-nitro-1H-pyrazole-3-carboxylate, A new synthetic method of this compound is introduced below., name: Methyl 5-nitro-1H-pyrazole-3-carboxylate\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=5497\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"New learning discoveries about\" \/>\n<meta property=\"og:description\" content=\"Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. 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