{"id":5395,"date":"2021-07-16T03:28:07","date_gmt":"2021-07-15T19:28:07","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=5395"},"modified":"2021-07-16T03:28:07","modified_gmt":"2021-07-15T19:28:07","slug":"extended-knowledge-of-13-dimethyl-1h-thieno23-cpyrazole-5-carboxylic-acid","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=5395","title":{"rendered":"Extended knowledge of 1,3-Dimethyl-1H-thieno[2,3-c]pyrazole-5-carboxylic acid"},"content":{"rendered":"

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 25252-46-4, name is 1,3-Dimethyl-1H-thieno[2,3-c]pyrazole-5-carboxylic acid, This compound has unique chemical properties. The synthetic route is as follows., Recommanded Product: 25252-46-4<\/a><\/p>\n

N-methoxy-N,1,3-trimethyl-1H-thieno[2,3-c]pyrazole-5-carboxamide A solution of 1,3-dimethyl-1H-thieno[2,3-c]pyrazole-5-carboxylic acid (2 g, 10.19 mmol, 1.00 equiv) methoxy(methyl)amine hydrochloride (1.06 g, 10.87 mmol, 1.10 equiv), DIEA (4 g, 30.95 mmol, 3.00 equiv), and HATU (5.8 g, 15.26 mmol, 1.50 equiv) in DMF (30 mL) was stirred for 2 h at rt, diluted with 100 mL of water, and extracted with 2\u00d7100 mL of EtOAc. The combined organic layers were washed with 100 mL brine, dried over Na2SO4, concentrated under vacuum, and purified with silica gel chromatography using EtOAc\/petroleum ether (1:3) to afford 2.2 g (90%) of the title compound as a yellow solid. LC-MS: (ES, m\/z): 240<\/p>\n

According to the analysis of related databases, 25252-46-4, the application of this compound in the production field has become more and more popular.<\/p>\n

Reference:
Patent; Vettore, LLC; PARNELL, Kenneth Mark; MCCALL, John; ROMERO, Donna; (172 pag.)US2018\/162822; (2018); A1;<\/a>,
Pyrazole – Wikipedia<\/a>,
Pyrazoles – an overview | ScienceDirect Topics<\/p>\n","protected":false},"excerpt":{"rendered":"

According to the analysis of related databases, 25252-46-4, the application of this compound in the production field has become more and more popular.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[711,131],"tags":[126],"class_list":["post-5395","post","type-post","status-publish","format-standard","hentry","category-25252-46-4","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nExtended knowledge of<\/title>\n<meta name=\"description\" content=\"Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 25252-46-4, name is 1,3-Dimethyl-1H-thieno[2,3-c]pyrazole-5-carboxylic acid, This compound has unique chemical properties. The synthetic route is as follows., Recommanded Product: 25252-46-4\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=5395\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Extended knowledge of\" \/>\n<meta property=\"og:description\" content=\"Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 25252-46-4, name is 1,3-Dimethyl-1H-thieno[2,3-c]pyrazole-5-carboxylic acid, This compound has unique chemical properties. 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