{"id":5363,"date":"2021-07-14T03:26:47","date_gmt":"2021-07-13T19:26:47","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=5363"},"modified":"2021-07-14T03:26:47","modified_gmt":"2021-07-13T19:26:47","slug":"extended-knowledge-of-c4h5brn2","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=5363","title":{"rendered":"Extended knowledge of C4H5BrN2"},"content":{"rendered":"

In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 13808-64-5, name is 4-Bromo-3-methylpyrazole belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below. COA of Formula: C4H5BrN2<\/a><\/p>\n

Step A: N-Boc-4-bromo-3-methyl-pyrazole. To 4-bromo-3-methyl-pyrazole (3.50 g, 21.7 mmol) was added CH2Cl2 (30 mL), di-tert-butyl dicarbonate (5.22 g, 23.9 mmol) and aq Na2CO3 (1 M, 43.5 mL). The reaction was stirred for 2.5 h and the aq portion was then separated. The CH2Cl2 portion was then washed with 5% citric acid followed by brine\/saturated aq NaHCO3 (1:1). The solution was dried (Na2SO4), filtered and concentrated to afford the product.<\/p>\n

The synthetic route of 13808-64-5 has been constantly updated, and we look forward to future research findings.<\/p>\n

Reference:
Patent; Clements, Matthew J.; Debenham, John S.; Hale, Jeffrey J.; Madsen-Duggan, Christina B.; Walsh, Thomas F.; Peresypkin, Andrey V.; Helmy, Roy; US2008\/269279; (2008); A1;<\/a>,
Pyrazole – Wikipedia<\/a>,
Pyrazoles – an overview | ScienceDirect Topics<\/p>\n","protected":false},"excerpt":{"rendered":"

The synthetic route of 13808-64-5 has been constantly updated, and we look forward to future research findings.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[240,131],"tags":[126],"class_list":["post-5363","post","type-post","status-publish","format-standard","hentry","category-13808-64-5","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nExtended knowledge of<\/title>\n<meta name=\"description\" content=\"In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 13808-64-5, name is 4-Bromo-3-methylpyrazole belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below. 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