{"id":5267,"date":"2021-07-09T03:42:35","date_gmt":"2021-07-08T19:42:35","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=5267"},"modified":"2021-07-09T03:42:35","modified_gmt":"2021-07-08T19:42:35","slug":"the-origin-of-a-common-compound-about-1082745-50-3-2","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=5267","title":{"rendered":"The origin of a common compound about 1082745-50-3"},"content":{"rendered":"

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 1082745-50-3, name is 5-Amino-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazole-4-carboxamide, This compound has unique chemical properties. The synthetic route is as follows., Formula: C9H14N4O2<\/a><\/p>\n

To a solution of 5-amino-1-tetrahydropyran-4-yl-pyrazole-4-carboxamide (4.78 g, 22.7mmol) in dry THF (200 mL) was added methyl 2-(4-bromophenyl)acetate (7.81 g, 34.1 mmol) and t-BuOK (1 M, 45 mL) in THF (45 mL). The mixture was stirred at 80C for 16 hours. Themixture was quenched with water (30 mL) and adjusted with HCI (iN, aqueous) to pH=7. The mixture was filtered. The filter cake was washed with water (20 mL x 3) to give 6-[(4- bromophenyl)methyl]-1-tetrahydropyran-4-yl-5H-pyrazolo[3,4-d]pyrimidin-4-one (5 g).<\/p>\n

According to the analysis of related databases, 1082745-50-3, the application of this compound in the production field has become more and more popular.<\/p>\n

Reference:
Patent; H. LUNDBECK A\/S; KEHLER, Jan; RASMUSSEN, Lars, Kyhn; LANGGARD, Morten; JESSING, Mikkel; VITAL, Paulo, Jorge, Vieira; JUHL, Karsten; (87 pag.)WO2018\/73251; (2018); A1;<\/a>,
Pyrazole – Wikipedia<\/a>,
Pyrazoles – an overview | ScienceDirect Topics<\/p>\n","protected":false},"excerpt":{"rendered":"

According to the analysis of related databases, 1082745-50-3, the application of this compound in the production field has become more and more popular.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[414,131],"tags":[127],"class_list":["post-5267","post","type-post","status-publish","format-standard","hentry","category-1082745-50-3","category-pyrazoles-derivatives","tag-m-w200-300"],"yoast_head":"\nThe origin of a common compound about<\/title>\n<meta name=\"description\" content=\"Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 1082745-50-3, name is 5-Amino-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazole-4-carboxamide, This compound has unique chemical properties. The synthetic route is as follows., Formula: C9H14N4O2\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=5267\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"The origin of a common compound about\" \/>\n<meta property=\"og:description\" content=\"Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 1082745-50-3, name is 5-Amino-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazole-4-carboxamide, This compound has unique chemical properties. 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