{"id":5125,"date":"2021-07-02T03:52:03","date_gmt":"2021-07-01T19:52:03","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=5125"},"modified":"2021-07-02T03:52:03","modified_gmt":"2021-07-01T19:52:03","slug":"the-important-role-of-37622-90-5-3","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=5125","title":{"rendered":"The important role of 37622-90-5"},"content":{"rendered":"

Related Products of 37622-90-5<\/a>, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 37622-90-5, name is Ethyl 4-pyrazolecarboxylate belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below.<\/p>\n

l-(Chloromethyl)-4-methoxybenzene (157 mmol, 24.5 g) and K2CO3 (39.43 g, 285.71 mmol) were added to a solution of ethyl lH-pyrazole-4- carboxylate (143 mmol, 20.0 g) in acetonitrile (150 mL). The resulting mixture was stirred under reflux for 5 h. After cooling to rt, the mixture was filtered and concentrated in vacuum. The residue was purified by flash chromatography over silica gel using EtOAc\/PE ( 1 :20 to -1 :5) as eluent to afford ethyl l-(4-methoxybenzyl)-lH- pyrazole-4-carboxylate ( 126.7 mmol, 33 g, 89%) as an off-white solid. LC-MS: m\/z ES = 261.<\/p>\n

The synthetic route of Ethyl 4-pyrazolecarboxylate has been constantly updated, and we look forward to future research findings.<\/p>\n

Reference:
Patent; ADDEX PHARMA S.A.; BOLEA, Christelle; CELANIRE, Sylvain; BOUDOU, Cedric; TANG, Lam; ROCHER, Jean-Philippe; LIVERTON, Nigel, J.; WO2012\/9009; (2012); A2;<\/a>,
Pyrazole – Wikipedia<\/a>,
Pyrazoles – an overview | ScienceDirect Topics<\/p>\n","protected":false},"excerpt":{"rendered":"

The synthetic route of Ethyl 4-pyrazolecarboxylate has been constantly updated, and we look forward to future research findings.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[218,131],"tags":[126],"class_list":["post-5125","post","type-post","status-publish","format-standard","hentry","category-37622-90-5","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nThe important role of<\/title>\n<meta name=\"description\" content=\"Related Products of 37622-90-5, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 37622-90-5, name is Ethyl 4-pyrazolecarboxylate belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=5125\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"The important role of\" \/>\n<meta property=\"og:description\" content=\"Related Products of 37622-90-5, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 37622-90-5, name is Ethyl 4-pyrazolecarboxylate belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.pyrazoles-derivatives.com\/?p=5125\" \/>\n<meta property=\"og:site_name\" content=\"pyrazoles-derivatives\" \/>\n<meta property=\"article:published_time\" content=\"2021-07-01T19:52:03+00:00\" \/>\n<meta name=\"author\" content=\"Jessica.F\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jessica.F\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=5125\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=5125\",\"name\":\"The important role of\",\"isPartOf\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\"},\"datePublished\":\"2021-07-01T19:52:03+00:00\",\"author\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\"},\"description\":\"Related Products of 37622-90-5, In the next few decades, the world population will flourish. 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