{"id":5092,"date":"2021-07-01T03:37:21","date_gmt":"2021-06-30T19:37:21","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=5092"},"modified":"2021-07-01T03:37:21","modified_gmt":"2021-06-30T19:37:21","slug":"analyzing-the-synthesis-route-of-37622-90-5","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=5092","title":{"rendered":"Analyzing the synthesis route of 37622-90-5"},"content":{"rendered":"

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 37622-90-5, name is Ethyl 4-pyrazolecarboxylate, A new synthetic method of this compound is introduced below., Application In Synthesis of Ethyl 4-pyrazolecarboxylate<\/a><\/p>\n

To a soution of ethyM H pyrazoe4carboxyate (450 mg, 315 mmo) in acetone (63 m) K2C03 (976 mg, T06mmo), 2(choromethy)pyridine hydrochbride (516 mg, 315 mmo) and TBA (119 mg, 032 mmo) was added. The mxture was heated at 6000 overnight. The reaction mixture was cooked and ffltered to remove any soHds. The fitrate was concentrated. Purificaflon by flash chromatography, sflica g&, gradient hexane to ethy acetate afforded the desired product (605 mg, 83% yied) as yeNow oiL 1HNMR (300MHz,CD3), oe ppm: 857 (d, J = 5 Hz, 1H), 803 (s, 1H), 794 (s, 1H), 765 (td, J = 8, 2 Hz,1H), T22 (dd, J = 8,5Hz, 1H), 711 (d, J = 8Hz, 1H), 545 (s, 2H), 430 (q, J 7Hz,2H), t34 (t, J 7 Hz, 3H).<\/p>\n

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.<\/p>\n

Reference:
Patent; LABORATORIOS DEL DR. ESTEVE, S.A.; CUEVAS CORDOBES, Felix; ALMANSA-ROSALES, Carmen; GARCIA LOPEZ, Monica; WO2015\/91939; (2015); A1;<\/a>,
Pyrazole – Wikipedia<\/a>,
Pyrazoles – an overview | ScienceDirect Topics<\/p>\n","protected":false},"excerpt":{"rendered":"

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[218,131],"tags":[126],"class_list":["post-5092","post","type-post","status-publish","format-standard","hentry","category-37622-90-5","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nAnalyzing the synthesis route of<\/title>\n<meta name=\"description\" content=\"Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. 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