{"id":5086,"date":"2021-07-01T03:37:21","date_gmt":"2021-06-30T19:37:21","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=5086"},"modified":"2021-07-01T03:37:21","modified_gmt":"2021-06-30T19:37:21","slug":"introduction-of-a-new-synthetic-route-about-4149-06-8-2","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=5086","title":{"rendered":"Introduction of a new synthetic route about 4149-06-8"},"content":{"rendered":"

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 4149-06-8, name is 3-Amino-1-phenyl-1H-pyrazol-5(4H)-one, This compound has unique chemical properties. The synthetic route is as follows., Quality Control of 3-Amino-1-phenyl-1H-pyrazol-5(4H)-one<\/a><\/p>\n

General procedure: A mixture of substituted 3-(2-aryl-2-oxoethylidene)indolin-2-one 1 (1 mmol), 1,3-dimethylurea (2, 1.2 mmol) or 5-amino-2-phenyl-2,4-dihydro-3H-pyrazol-3-one (4, 1 mmol), PTSA\u00b7H2O (0.3 mmol), and MeCN (5 mL) was added to a 25 mL flask and reacted at 80 C (monitored by TLC) about 2 h. After completion, the mixture was cooled to r.t. and the precipitate obtained was isolated by filtration and drying. Compounds 3 or 5 were purified by recrystallization (DMF or EtOH).<\/p>\n

According to the analysis of related databases, 4149-06-8, the application of this compound in the production field has become more and more popular.<\/p>\n

Reference:
Article; Dai, Lei; Shu, Ping; Wang, Zhansheng; Li, Qingyang; Yu, Qiuyu; Shi, Yanhui; Rong, Liangce; Synthesis; vol. 49; 3; (2017); p. 637 – 646;<\/a>,
Pyrazole – Wikipedia<\/a>,
Pyrazoles – an overview | ScienceDirect Topics<\/p>\n","protected":false},"excerpt":{"rendered":"

According to the analysis of related databases, 4149-06-8, the application of this compound in the production field has become more and more popular.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[283,131],"tags":[126],"class_list":["post-5086","post","type-post","status-publish","format-standard","hentry","category-4149-06-8","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nIntroduction of a new synthetic route about<\/title>\n<meta name=\"description\" content=\"Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 4149-06-8, name is 3-Amino-1-phenyl-1H-pyrazol-5(4H)-one, This compound has unique chemical properties. 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