{"id":5023,"date":"2021-06-29T03:13:51","date_gmt":"2021-06-28T19:13:51","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=5023"},"modified":"2021-06-29T03:13:51","modified_gmt":"2021-06-28T19:13:51","slug":"continuously-updated-synthesis-method-about-2-1h-pyrazol-3-ylpyridine","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=5023","title":{"rendered":"Continuously updated synthesis method about 2-(1H-Pyrazol-3-yl)pyridine"},"content":{"rendered":"

Synthetic Route of 75415-03-1<\/a>, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 75415-03-1, name is 2-(1H-Pyrazol-3-yl)pyridine belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below.<\/p>\n

Example 16 Synthesis of 2-(1-(2-fluoro-4-nitrophenyl)-3-pyrazolyl)pyridine (18a) Compound 17a (1 g, 6.9 mmol) obtained from the aforesaid process and 3,4-difluoronitrobenzene (0.74 mL) were dissolved in N,N-dimethylformamide (20 mL), and then anhydrous potassium carbonate (1.9 g) was added thereto. The mixture was reacted at 100 C for 4 hours. After completion of the reaction, the reactant mixture was cooled to room temperature. Water was added to the mixture, resulting in a substantial amount of precipitate. Then, the precipitate wassuction-filtered, and the filter cake was recrystallized with acetone to get the product 18a as a white powder (1.7 g), witha yield of 93.4%.[0110] 1H-NMR (400 MHz, CDCl3 ): delta 8.69-8.70 (m, 1H), 8.39-8.44 (m, 1H), 8.26-8.27 (m, 1H), 8.15-8.21 (m, 2H),8.11-8.13 (m, 1H), 7.78-7.82 (m, 1H), 7.30-7.32 (m, 1H), 7.22 (d, J= 2.4 Hz, 1H)<\/p>\n

The synthetic route of 2-(1H-Pyrazol-3-yl)pyridine has been constantly updated, and we look forward to future research findings.<\/p>\n

Reference:
Patent; SICHUAN GOODDOCTOR PHARMACEUTICAL GROUP CO., LTD.; Si Chuan University; LUO, Youfu; WANG, Zhenling; WEI, Yuquan; GENG, Funeng; EP2738169; (2014); A1;<\/a>,
Pyrazole – Wikipedia<\/a>,
Pyrazoles – an overview | ScienceDirect Topics<\/p>\n","protected":false},"excerpt":{"rendered":"

The synthetic route of 2-(1H-Pyrazol-3-yl)pyridine has been constantly updated, and we look forward to future research findings.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[225,131],"tags":[126],"class_list":["post-5023","post","type-post","status-publish","format-standard","hentry","category-75415-03-1","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nContinuously updated synthesis method about<\/title>\n<meta name=\"description\" content=\"Synthetic Route of 75415-03-1, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 75415-03-1, name is 2-(1H-Pyrazol-3-yl)pyridine belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=5023\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Continuously updated synthesis method about\" \/>\n<meta property=\"og:description\" content=\"Synthetic Route of 75415-03-1, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 75415-03-1, name is 2-(1H-Pyrazol-3-yl)pyridine belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.pyrazoles-derivatives.com\/?p=5023\" \/>\n<meta property=\"og:site_name\" content=\"pyrazoles-derivatives\" \/>\n<meta property=\"article:published_time\" content=\"2021-06-28T19:13:51+00:00\" \/>\n<meta name=\"author\" content=\"Jessica.F\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jessica.F\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=5023\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=5023\",\"name\":\"Continuously updated synthesis method about\",\"isPartOf\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\"},\"datePublished\":\"2021-06-28T19:13:51+00:00\",\"author\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\"},\"description\":\"Synthetic Route of 75415-03-1, In the next few decades, the world population will flourish. 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