{"id":4985,"date":"2021-06-28T03:46:57","date_gmt":"2021-06-27T19:46:57","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=4985"},"modified":"2021-06-28T03:46:57","modified_gmt":"2021-06-27T19:46:57","slug":"extended-knowledge-of-tert-butyl-tert-butoxycarbonylamino1h-pyrazol-1-ylmethylenecarbamate","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=4985","title":{"rendered":"Extended knowledge of tert-Butyl (((tert-butoxycarbonyl)amino)(1H-pyrazol-1-yl)methylene)carbamate"},"content":{"rendered":"

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 152120-54-2, name is tert-Butyl (((tert-butoxycarbonyl)amino)(1H-pyrazol-1-yl)methylene)carbamate, This compound has unique chemical properties. The synthetic route is as follows., Computed Properties of C14H22N4O4<\/a><\/p>\n

4-(Dimethylamino)pyridine (660 mg, 5.41 mmol) was added to a solution of tert- butyl(((tert-butoxycarbonyl)imino)(lH-pyrazol-l-yl)methyl)carbamate (11.37 g, 54.1 mmol, 1.0 equiv.) in dichloromethane (60 mL). Di-tert-butyldicarbonate (23.61 g, 108.2 mmol, 2.0 equiv.) in THF (40.0 mL) was slowly added over the course of 8 h using a syringe pump. The solution was stirred overnight at room temperature, before the solvents were removed in vacuo. The resulting colorless solid was stirred in dilute acetic acid solution (0.52 g, 8.66 mmol, acetic acid in 60 mL water). The precipitated tert-butyl tert-butoxycarbonyl(((tert-butoxycarbonyl)imino)( 1 H-pyrazol- 1 -yl)methyl)carbamate was collected, washed with water, hexane, and dried in vacuo to yield a colorless solide (20.21 g, 91% yield). FontWeight=”Bold” FontSize=”10″ H NMR (CDCb, 400 MHz): delta 8.20 (d, J= 2.4 Hz, 1H), 7.69 (d, J= 0.8 Hz, 1H), 6.45 (dd, J= 2.8, 1.6 Hz, 1H), 1.54 (s, 9H), 1.39 (s, 18H).<\/p>\n

According to the analysis of related databases, 152120-54-2, the application of this compound in the production field has become more and more popular.<\/p>\n

Reference:
Patent; NUTECH VENTURES; DIMAGNO, Stephen; HU, Bao; WO2015\/147950; (2015); A2;<\/a>,
Pyrazole – Wikipedia<\/a>,
Pyrazoles – an overview | ScienceDirect Topics<\/p>\n","protected":false},"excerpt":{"rendered":"

According to the analysis of related databases, 152120-54-2, the application of this compound in the production field has become more and more popular.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[254,131],"tags":[167],"class_list":["post-4985","post","type-post","status-publish","format-standard","hentry","category-152120-54-2","category-pyrazoles-derivatives","tag-m-w300-400"],"yoast_head":"\nExtended knowledge of<\/title>\n<meta name=\"description\" content=\"Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 152120-54-2, name is tert-Butyl (((tert-butoxycarbonyl)amino)(1H-pyrazol-1-yl)methylene)carbamate, This compound has unique chemical properties. The synthetic route is as follows., Computed Properties of C14H22N4O4\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"http:\/\/www.pyrazoles-derivatives.com\/?p=4985\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Extended knowledge of\" \/>\n<meta property=\"og:description\" content=\"Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 152120-54-2, name is tert-Butyl (((tert-butoxycarbonyl)amino)(1H-pyrazol-1-yl)methylene)carbamate, This compound has unique chemical properties. 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Pyrazole derivatives play an important role in antitumor agents.\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\",\"name\":\"Jessica.F\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"caption\":\"Jessica.F\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Extended knowledge of","description":"Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 152120-54-2, name is tert-Butyl (((tert-butoxycarbonyl)amino)(1H-pyrazol-1-yl)methylene)carbamate, This compound has unique chemical properties. 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