{"id":4923,"date":"2021-06-24T04:24:34","date_gmt":"2021-06-23T20:24:34","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=4923"},"modified":"2021-06-24T04:24:34","modified_gmt":"2021-06-23T20:24:34","slug":"extended-knowledge-of-15001-11-3","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=4923","title":{"rendered":"Extended knowledge of 15001-11-3"},"content":{"rendered":"

In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 15001-11-3, name is Ethyl 5-amino-1-(p-tolyl)-1H-pyrazole-4-carboxylate belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below. Computed Properties of C13H15N3O2<\/a><\/p>\n

General procedure: Intermediate 4 (0.001mol) and 5 (0.001mol) were dissolved in pyridine, phosphorus oxychloride is slowly added dropwise under ice bath conditions, then at 40-60C reacted for 5-8h. Finally, the mixture was poured into 30mL saturated Na2CO3 solution and stirred well. After the mixture was acidified, the saturated CuSO4 solution was used to remove pyridine, which greatly improved the purity and yield of the product. The data for compounds 8I-8VI are provided in the supporting information.<\/p>\n

The synthetic route of 15001-11-3 has been constantly updated, and we look forward to future research findings.<\/p>\n

Reference:
Article; Liu, Hao; Ren, Zi-Li; Wang, Wei; Gong, Jie-Xiu; Chu, Ming-Jie; Ma, Quan-Wei; Wang, Jie-Chun; Lv, Xian-Hai; European Journal of Medicinal Chemistry; vol. 157; (2018); p. 81 – 87;<\/a>,
Pyrazole – Wikipedia<\/a>,
Pyrazoles – an overview | ScienceDirect Topics<\/p>\n","protected":false},"excerpt":{"rendered":"

The synthetic route of 15001-11-3 has been constantly updated, and we look forward to future research findings.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[630,131],"tags":[127],"class_list":["post-4923","post","type-post","status-publish","format-standard","hentry","category-15001-11-3","category-pyrazoles-derivatives","tag-m-w200-300"],"yoast_head":"\nExtended knowledge of<\/title>\n<meta name=\"description\" content=\"In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 15001-11-3, name is Ethyl 5-amino-1-(p-tolyl)-1H-pyrazole-4-carboxylate belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below. 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