{"id":4839,"date":"2021-06-21T04:01:03","date_gmt":"2021-06-20T20:01:03","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=4839"},"modified":"2021-06-21T04:01:03","modified_gmt":"2021-06-20T20:01:03","slug":"new-learning-discoveries-about-c4h3n3o4","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=4839","title":{"rendered":"New learning discoveries about C4H3N3O4"},"content":{"rendered":"

Related Products of 5334-40-7<\/a>, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 5334-40-7, name is 4-Nitro-1H-pyrazole-3-carboxylic acid belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below.<\/p>\n

Step 2. Synthesis of 4-nitro-1H-pyrazole-3-carboxylic acid (trans-4- methoxymethoxy-cvclohexyl)-amideA mixture of 4-nitro-3-pyrazolecarboxylic acid (2.32 g, 14.8 mmol), trans 4- aminocyclohexanol (2.95 g, 18.5 mmol), EDAC (3.55 g, 18.5 mmol) and HOBt (2.50 g, 18.5 mmol) in DMF (75 ml) was stirred at ambient temperature for 16 hours. The mixture was reduced in vacuo, partitioned between saturated aqueous sodium bicarbonate and ethyl acetate. The organic layer was washed (water, brine) dried (MgSO4), and reduced in vacuo to give a yellow oil (3.25 g), which was purified by column chromatography, eluting 0-100 percent EtOAc in petroleum ether, then 1-25 percent MeOH in EtOAc to give 4-nitro-1H-pyrazole-3-carboxylic acid (trans- 4-methoxymethoxy-cyclohexyl)-amide as a pale yellow solid (1.25 g). (LC\/MS: Rt 2.11 [M+H]+ 297.25).<\/p>\n

The synthetic route of 4-Nitro-1H-pyrazole-3-carboxylic acid has been constantly updated, and we look forward to future research findings.<\/p>\n

Reference:
Patent; ASTEX THERAPEUTICS LIMITED; WO2006\/77414; (2006); A1;<\/a>,
Pyrazole – Wikipedia<\/a>,
Pyrazoles – an overview | ScienceDirect Topics<\/p>\n","protected":false},"excerpt":{"rendered":"

The synthetic route of 4-Nitro-1H-pyrazole-3-carboxylic acid has been constantly updated, and we look forward to future research findings.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[153,131],"tags":[126],"class_list":["post-4839","post","type-post","status-publish","format-standard","hentry","category-5334-40-7","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nNew learning discoveries about<\/title>\n<meta name=\"description\" content=\"Related Products of 5334-40-7, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 5334-40-7, name is 4-Nitro-1H-pyrazole-3-carboxylic acid belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"http:\/\/www.pyrazoles-derivatives.com\/?p=4839\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"New learning discoveries about\" \/>\n<meta property=\"og:description\" content=\"Related Products of 5334-40-7, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 5334-40-7, name is 4-Nitro-1H-pyrazole-3-carboxylic acid belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below.\" \/>\n<meta property=\"og:url\" content=\"http:\/\/www.pyrazoles-derivatives.com\/?p=4839\" \/>\n<meta property=\"og:site_name\" content=\"pyrazoles-derivatives\" \/>\n<meta property=\"article:published_time\" content=\"2021-06-20T20:01:03+00:00\" \/>\n<meta name=\"author\" content=\"Jessica.F\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jessica.F\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/?p=4839\",\"url\":\"http:\/\/www.pyrazoles-derivatives.com\/?p=4839\",\"name\":\"New learning discoveries about\",\"isPartOf\":{\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/#website\"},\"datePublished\":\"2021-06-20T20:01:03+00:00\",\"author\":{\"@id\":\"http:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\"},\"description\":\"Related Products of 5334-40-7, In the next few decades, the world population will flourish. 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