{"id":4770,"date":"2021-06-17T03:31:01","date_gmt":"2021-06-16T19:31:01","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=4770"},"modified":"2021-06-17T03:31:01","modified_gmt":"2021-06-16T19:31:01","slug":"some-scientific-research-about-c9h12n2o2","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=4770","title":{"rendered":"Some scientific research about C9H12N2O2"},"content":{"rendered":"<p><a href=\"https:\/\/www.ambeed.com\/products\/86477-09-0.html\">Reference of 86477-09-0<\/a>, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 86477-09-0 as follows.<\/p>\n<p>Example 162a 5,6-Dihydro-4H-pyrrolo[1,2-b]pyrazole-2-carboxylic Acid 162a A 25-mL round-bottomed flask equipped with a reflux condenser was charged with ethyl 5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole-2-carboxylate (540 mg, 3.0 mmol), 2N Aqueous sodium hydroxide solution (3.5 mL), and 1,4-dioxane (3.0 mL). The system was heated at 65 C. for 2.5 h. It was then cooled to room temperature and adjusted the pH to 2-3 with concentrated HCl. The solid was collected by filtration to afford 162a (260 mg, 57%) as a yellow solid. MS-ESI: [M+H]+ 153.3<\/p>\n<p>According to the analysis of related databases, 86477-09-0, the application of this compound in the production field has become more and more popular.<\/p>\n<p>Reference:<br \/><a href=\"http:\/\/v3.espacenet.com\/textdoc?DB=EPODOC&#038;IDX=CN108948019&#038;F=0\">Patent; GENENTECH, INC.; Crawford, James John; Ortwine, Daniel Fred; Wei, BinQing; Young, Wendy B.; US2013\/116246; (2013); A1;<\/a>,<br \/><a href=\"https:\/\/en.wikipedia.org\/wiki\/Pyrazole\">Pyrazole &#8211; Wikipedia<\/a>,<br \/><a href=\"https:\/\/www.sciencedirect.com\/topics\/chemistry\/pyrazoles\">Pyrazoles &#8211; an overview | ScienceDirect Topics<\/p>\n","protected":false},"excerpt":{"rendered":"<p>According to the analysis of related databases, 86477-09-0, the application of this compound in the production field has become more and more popular.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[407,131],"tags":[126],"class_list":["post-4770","post","type-post","status-publish","format-standard","hentry","category-86477-09-0","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Some scientific research about<\/title>\n<meta name=\"description\" content=\"Reference of 86477-09-0, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. 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