{"id":4726,"date":"2021-06-16T04:23:46","date_gmt":"2021-06-15T20:23:46","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=4726"},"modified":"2021-06-16T04:23:46","modified_gmt":"2021-06-15T20:23:46","slug":"extended-knowledge-of-37687-18-6","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=4726","title":{"rendered":"Extended knowledge of 37687-18-6"},"content":{"rendered":"

Reference of 37687-18-6<\/a>, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 37687-18-6 as follows.<\/p>\n

1-(1-Methyl-1H-pyrazol-4-yl)ethanone (18 g, 145 mmol) and NBS (31 g, 174 mmol) were added to the reaction flask.Add CCl4 (80 mL) to dissolve, and add AIBN (2.4 g, 14.5 mmol) in portions under reflux, and react under 365 nm UV irradiation for 24 h.After the reaction is completed, the system is poured into ice water, extracted with dichloromethane, dried over anhydrous sodium sulfate, and the solvent is removed for column chromatography.(eluent: Petroleum ether\/EtOAc (v\/v) = 5\/1),5.9 g of a yellow oily product were obtained in a yield: 20%.<\/p>\n

According to the analysis of related databases, 37687-18-6, the application of this compound in the production field has become more and more popular.<\/p>\n

Reference:
Patent; Dongguan Dongyang Guang Ke Research And Development Co., Ltd.; Li Yitao; Lin Jian; Chi Weilin; Zeng Shuiming; (43 pag.)CN110294747; (2019); A;<\/a>,
Pyrazole – Wikipedia<\/a>,
Pyrazoles – an overview | ScienceDirect Topics<\/p>\n","protected":false},"excerpt":{"rendered":"

According to the analysis of related databases, 37687-18-6, the application of this compound in the production field has become more and more popular.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[531,131],"tags":[126],"class_list":["post-4726","post","type-post","status-publish","format-standard","hentry","category-37687-18-6","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nExtended knowledge of<\/title>\n<meta name=\"description\" content=\"Reference of 37687-18-6, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. 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