{"id":4706,"date":"2021-06-15T04:35:52","date_gmt":"2021-06-14T20:35:52","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=4706"},"modified":"2021-06-15T04:35:52","modified_gmt":"2021-06-14T20:35:52","slug":"extended-knowledge-of-c6h8n2o2-2","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=4706","title":{"rendered":"Extended knowledge of C6H8N2O2"},"content":{"rendered":"

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 23170-45-8, name is Methyl 3-methyl-1H-pyrazole-4-carboxylate, This compound has unique chemical properties. The synthetic route is as follows., Recommanded Product: 23170-45-8<\/a><\/p>\n

General procedure: Compound (11a-g or 12f-g) (1.2 mmol), CuI (19.1 mg, 0.1 mmol), trans-N,N’-dimethyl-1,2-cyclohexane-diamine (29 mg, 0.2 mmol), K2CO3 (0.29 g, 2.1 mmol) and DMF (3 mL) were added to a tube filled with argon. The mixture was stirred at 110 C for 24 h. The reaction was diluted with H2O (20 mL) and extracted with EtOAc (15 mL x 2). The combined organic phases were washed with H2O (20 mL x 2) and brine (30 mL), dried over MgSO4 and concentratedin a vacuum. The residue was purified by flash column chromatography (12-25% EtOAc in petroleum ether).<\/p>\n

According to the analysis of related databases, 23170-45-8, the application of this compound in the production field has become more and more popular.<\/p>\n

Reference:
Article; Li, Jing; Wu, Fangping; Liu, Xingguo; Zou, Yake; Chen, Huixiong; Li, Zheng; Zhang, Lei; European Journal of Medicinal Chemistry; vol. 140; (2017); p. 20 – 30;<\/a>,
Pyrazole – Wikipedia<\/a>,
Pyrazoles – an overview | ScienceDirect Topics<\/p>\n","protected":false},"excerpt":{"rendered":"

According to the analysis of related databases, 23170-45-8, the application of this compound in the production field has become more and more popular.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[397,131],"tags":[126],"class_list":["post-4706","post","type-post","status-publish","format-standard","hentry","category-23170-45-8","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nExtended knowledge of<\/title>\n<meta name=\"description\" content=\"Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 23170-45-8, name is Methyl 3-methyl-1H-pyrazole-4-carboxylate, This compound has unique chemical properties. 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