{"id":4468,"date":"2021-06-03T04:02:16","date_gmt":"2021-06-02T20:02:16","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=4468"},"modified":"2021-06-03T04:02:16","modified_gmt":"2021-06-02T20:02:16","slug":"analyzing-the-synthesis-route-of-c5h8brn3o2s","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=4468","title":{"rendered":"Analyzing the synthesis route of C5H8BrN3O2S"},"content":{"rendered":"

In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 500011-84-7 as follows. COA of Formula: C5H8BrN3O2S<\/a><\/p>\n

To trifluoroacetic acid (70 mL) was slowly added [3-BROMO N, N DIMETHYL-1H] [PYRAZOLE-L-SULFONAMIDE] (i. e. the bromopyrazole product of Step B) (57.04 g). The reaction mixture was stirred at room temperature for 30 minutes and then concentrated at reduced pressure. The residue was taken up in hexane, insoluble solids were filtered off, and the hexane was evaporated to afford the crude product as an oil. The crude product was further purified by chromatography on silica gel using ethyl acetate\/dichloromethane (10: 90) as eluent to afford an oil. The oil was taken up in dichloromethane, neutralized with aqueous sodium bicarbonate solution, extracted with dichloromethane [(3X),] dried over magnesium sulfate and concentrated to afford the title product as a white solid (25.9 g), m. p. [61-64 C.] 1H NMR (CDC13) 8 6.37 (d, 1H), 7.59 (d, 1H), 12.4 (br s, 1H).<\/p>\n

According to the analysis of related databases, 500011-84-7, the application of this compound in the production field has become more and more popular.<\/p>\n

Reference:
Patent; E.I. DU PONT DE NEMOURS AND COMPANY; WO2004\/11447; (2004); A2;<\/a>,
Pyrazole – Wikipedia<\/a>,
Pyrazoles – an overview | ScienceDirect Topics<\/p>\n","protected":false},"excerpt":{"rendered":"

According to the analysis of related databases, 500011-84-7, the application of this compound in the production field has become more and more popular.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[373,131],"tags":[127],"class_list":["post-4468","post","type-post","status-publish","format-standard","hentry","category-500011-84-7","category-pyrazoles-derivatives","tag-m-w200-300"],"yoast_head":"\nAnalyzing the synthesis route of<\/title>\n<meta name=\"description\" content=\"In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 500011-84-7 as follows. 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