{"id":4329,"date":"2021-05-27T03:57:15","date_gmt":"2021-05-26T19:57:15","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=4329"},"modified":"2021-05-27T03:57:15","modified_gmt":"2021-05-26T19:57:15","slug":"introduction-of-a-new-synthetic-route-about-5-methyl-1h-pyrazol-3-amine","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=4329","title":{"rendered":"Introduction of a new synthetic route about 5-Methyl-1H-pyrazol-3-amine"},"content":{"rendered":"

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 31230-17-8, name is 5-Methyl-1H-pyrazol-3-amine, A new synthetic method of this compound is introduced below., SDS of cas: 31230-17-8<\/a><\/p>\n

General procedure: A solution of 2,4-dichloroquinazoline (1.0 equiv.) in THF, triethylamine (1.2 equiv.) and alkylamine (1.2 equiv.) were added. The reaction stirred at room temperature until cannot see reactant spots on TLC. The solvent was removed by evaporated under reduced pressure, dissolved in ethyl acetate and washed with saturated sodium chloride and extracted. The organic layer was collected, dried over anhydrous sodium sulfate, filtered, and dried under vacuum to give the compound as a solid<\/p>\n

The synthetic route of 31230-17-8 has been constantly updated, and we look forward to future research findings.<\/p>\n

Reference:
Article; Pobsuk, Nattakarn; Paracha, Tamkeen Urooj; Chaichamnong, Nattiya; Salaloy, Nattapas; Suphakun, Praphasri; Hannongbua, Supa; Choowongkomon, Kiattawee; Pekthong, Dumrongsak; Chootip, Krongkarn; Ingkaninan, Kornkanok; Gleeson, M. Paul; Bioorganic and Medicinal Chemistry Letters; vol. 29; 2; (2019); p. 267 – 270;<\/a>,
Pyrazole – Wikipedia<\/a>,
Pyrazoles – an overview | ScienceDirect Topics<\/p>\n","protected":false},"excerpt":{"rendered":"

The synthetic route of 31230-17-8 has been constantly updated, and we look forward to future research findings.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[207,131],"tags":[145],"class_list":["post-4329","post","type-post","status-publish","format-standard","hentry","category-31230-17-8","category-pyrazoles-derivatives","tag-m-w0-100"],"yoast_head":"\nIntroduction of a new synthetic route about<\/title>\n<meta name=\"description\" content=\"Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. 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