{"id":4327,"date":"2021-05-27T03:57:15","date_gmt":"2021-05-26T19:57:15","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=4327"},"modified":"2021-05-27T03:57:15","modified_gmt":"2021-05-26T19:57:15","slug":"the-important-role-of-c5h5n3","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=4327","title":{"rendered":"The important role of C5H5N3"},"content":{"rendered":"

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 66121-71-9, name is 4-Cyano-1-methylpyrazole, This compound has unique chemical properties. The synthetic route is as follows., Quality Control of 4-Cyano-1-methylpyrazole<\/a><\/p>\n

Step 3: 5-( 1-methyl-I H-pyrazol-4-yI)-2H-tetrazole1-mcthyl-IH-pyrazole-4-carbonitrile (18 gm, 0.168 moles) obtained instep 2, tn-nbutyl tin chloride (65 gm, 0.218 moles), sodium azide (14 gm, 0.20 Imoles) were taken in toluene (180 ml). The reaction mixture was stirred for 24 hours at 110-120C. The progress of the reaction was monitored by HPLC. The above reaction mixture was cooled to 10-15C, to this added 10% ethanolic HC1 solution (100 ml, pH= 1-2). The reaction mixture was stirred for 1-1.5 hours at 10i5C, filtered off the inorganic salts, washed with ethanol (30 ml). Themother liquor and washings were collected and toluene and ethanol were recovered at 50-55C at reduced pressure. To the abOve residue at 20-25C, added di-isopropyl ether (100ml), stirred for 1-2 hours at 20-25C, filtered the solid, washed with.di-isopropyl ether (30ml) and dried at 60-65C to yield the product, 5-(1-methyl-1H-pyrazol-4-yl)-2H-tetrazole.Drywt 25gmYield 1.4 w\/w (99%)<\/p>\n

According to the analysis of related databases, 66121-71-9, the application of this compound in the production field has become more and more popular.<\/p>\n

Reference:
Patent; RALLIS INDIA LIMITED; PALIMKAR, Sanjay Sambhajirao; PAWAR, Jivan Dhanraj; SANKAR, B; KADAM, Subhash Rajaram; HINDUPUR, Rama Mohan; PRABHU, Venkatesh M; PATI, Hari Narayan; SUPHALA, Vadiraj Gopinath; MANE, Avinash Sheshrao; WO2014\/2110; (2014); A1;<\/a>,
Pyrazole – Wikipedia<\/a>,
Pyrazoles – an overview | ScienceDirect Topics<\/p>\n","protected":false},"excerpt":{"rendered":"

According to the analysis of related databases, 66121-71-9, the application of this compound in the production field has become more and more popular.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[525,131],"tags":[126],"class_list":["post-4327","post","type-post","status-publish","format-standard","hentry","category-66121-71-9","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nThe important role of<\/title>\n<meta name=\"description\" content=\"Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 66121-71-9, name is 4-Cyano-1-methylpyrazole, This compound has unique chemical properties. 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