{"id":4255,"date":"2021-05-25T04:07:47","date_gmt":"2021-05-24T20:07:47","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=4255"},"modified":"2021-05-25T04:07:47","modified_gmt":"2021-05-24T20:07:47","slug":"sources-of-common-compounds-c7h10n2o2-3","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=4255","title":{"rendered":"Sources of common compounds: C7H10N2O2"},"content":{"rendered":"<p><a href=\"https:\/\/www.ambeed.com\/products\/920006-32-2.html\">Electric Literature of 920006-32-2<\/a>, These common heterocyclic compound, 920006-32-2, name is 1-Isopropylpyrazole-5-carboxylic Acid, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.<\/p>\n<p>Intermediate 941 -(1 -Methylethyl)-1 H-pyrazole-5-carbonyl chloride Thionyl chloride (5 ml) was added to 1-(1-methylethyl)-1 H-pyrazole-5-carboxylic acid (1g) and the reaction was heated at 800C for 5h. The reaction was evaporated, then azeotroped with toluene to give title compound, 856mg. <n=\"133\"\/>1H NMR (CDCI3) delta 7.6 (d, 1 H), delta 7.1 (d, 1 H), delta 5.2 (m, 1 H), delta 1.5 (d, 6H).<\/p>\n<p>Statistics shows that 1-Isopropylpyrazole-5-carboxylic Acid is playing an increasingly important role. we look forward to future research findings about 920006-32-2.<\/p>\n<p>Reference:<br \/><a href=\"http:\/\/v3.espacenet.com\/textdoc?DB=EPODOC&#038;IDX=US2007032478&#038;F=0\">Patent; GLAXO GROUP LIMITED; WO2009\/147188; (2009); A1;<\/a>,<br \/><a href=\"https:\/\/en.wikipedia.org\/wiki\/Pyrazole\">Pyrazole &#8211; Wikipedia<\/a>,<br \/><a href=\"https:\/\/www.sciencedirect.com\/topics\/chemistry\/pyrazoles\">Pyrazoles &#8211; an overview | ScienceDirect Topics<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Statistics shows that 1-Isopropylpyrazole-5-carboxylic Acid is playing an increasingly important role. we look forward to future research findings about 920006-32-2.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[615,131],"tags":[126],"class_list":["post-4255","post","type-post","status-publish","format-standard","hentry","category-920006-32-2","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - 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