{"id":4230,"date":"2021-05-24T04:29:49","date_gmt":"2021-05-23T20:29:49","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=4230"},"modified":"2021-05-24T04:29:49","modified_gmt":"2021-05-23T20:29:49","slug":"application-of-c7h9brn2o2","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=4230","title":{"rendered":"Application of C7H9BrN2O2"},"content":{"rendered":"

In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 1269293-48-2, name is Ethyl 5-bromo-1-methyl-1H-pyrazole-3-carboxylate belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below. Recommanded Product: 1269293-48-2<\/a><\/p>\n

STEP A: 5-Bromo-1-methyl-1H-pyrazole-3-carboxylic acid [0180] Lithium hydroxide (8.58 mL, 17.16 mmol) was added to a mixture of ethyl 5- bromo-1 -methyl- lH-pyrazole-3-carboxylate (1 g, 4.29 mmol) in THF (10 mL) and water (2 mL). The reaction mixture was stirred for 5 hours at room temperature and was subsequently concentrated, acidified with concentrated HC1, and extracted into EtOAc. The organic layer was dried over Na2S04 and concentrated to give the title compound as a white solid (0.72 g, 82%).<\/p>\n

The synthetic route of 1269293-48-2 has been constantly updated, and we look forward to future research findings.<\/p>\n

Reference:
Patent; TAKEDA PHARMACEUTICAL COMPANY LIMITED; CHERUVALLATH, Zacharia; KOMANDLA, Mallareddy; LAWSON, John David; MCBRIDE, Christopher; TANG, Mingnam; WO2014\/39831; (2014); A1;<\/a>,
Pyrazole – Wikipedia<\/a>,
Pyrazoles – an overview | ScienceDirect Topics<\/p>\n","protected":false},"excerpt":{"rendered":"

The synthetic route of 1269293-48-2 has been constantly updated, and we look forward to future research findings.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[654,131],"tags":[127],"class_list":["post-4230","post","type-post","status-publish","format-standard","hentry","category-1269293-48-2","category-pyrazoles-derivatives","tag-m-w200-300"],"yoast_head":"\nApplication of<\/title>\n<meta name=\"description\" content=\"In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 1269293-48-2, name is Ethyl 5-bromo-1-methyl-1H-pyrazole-3-carboxylate belongs to pyrazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below. 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