{"id":4178,"date":"2021-05-21T03:39:14","date_gmt":"2021-05-20T19:39:14","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=4178"},"modified":"2021-05-21T03:39:14","modified_gmt":"2021-05-20T19:39:14","slug":"continuously-updated-synthesis-method-about-c7h12n2","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=4178","title":{"rendered":"Continuously updated synthesis method about C7H12N2"},"content":{"rendered":"

Adding a certain compound to certain chemical reactions, such as: 52096-24-9, name is 1-Butyl-1H-pyrazole, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 52096-24-9, Product Details of 52096-24-9<\/a><\/p>\n

Example 164 Preparation of 1-butyl-alpha-phenyl-1H-pyrazole-5-methanol A solution of 12.4 g of 1-butylpyrazole in 100 ml of absolute ether is placed in a three-necked flask provided with a stirrer, a condenser, a dropping adapter and a thermometer, it is cooled with ice and 6.1 g of a 1.6M solution of butyllithium in hexane are added slowly. The mixture is stirred for 30 minutes and a solution of 14.5 g of p-chlorobenzaldehyde in 30 ml of absolute ether is added slowly. After the reaction, stirring is continued until the mixture reaches room temperature, after which it is hydrolyzed with 100 ml of water. Extraction is carried out with benzene, the benzene phase is washed and dried over sodium sulfate and the solvent is removed in vacuo. This gives 18.9 g (82%) of an oil which can be crystallized from a methanol\/water mixture to give crystals melting at 46-7 C., the product being 1-butyl-alpha-phenyl -1H-pyrazole-5-methanol.<\/p>\n

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it.<\/p>\n

Reference:
Patent; Laboratorios del Dr. Esteve, S.A.; US5017596; (1991); A;<\/a>,
Pyrazole – Wikipedia<\/a>,
Pyrazoles – an overview | ScienceDirect Topics<\/p>\n","protected":false},"excerpt":{"rendered":"

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[687,131],"tags":[126],"class_list":["post-4178","post","type-post","status-publish","format-standard","hentry","category-52096-24-9","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nContinuously updated synthesis method about<\/title>\n<meta name=\"description\" content=\"Adding a certain compound to certain chemical reactions, such as: 52096-24-9, name is 1-Butyl-1H-pyrazole, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. 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