{"id":4166,"date":"2021-05-19T03:55:08","date_gmt":"2021-05-18T19:55:08","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=4166"},"modified":"2021-05-19T03:55:08","modified_gmt":"2021-05-18T19:55:08","slug":"some-tips-on-39205-87-3","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=4166","title":{"rendered":"Some tips on 39205-87-3"},"content":{"rendered":"

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 39205-87-3, name is 3-Nitro-1H-pyrazole-4-carbonitrile, A new synthetic method of this compound is introduced below., Formula: C4H2N4O2<\/a><\/p>\n

EXAMPLE 7 3-(1-Ethyl-3-nitro-4-pyrazolyl)-acrylic acid 20 g. 3-nitro-4-pyrazole-carbonitrile are stirred with 17.5 ml. ethyl iodide, 21 g. potassium carbonate and 145 ml. 1,2-dimethoxyethane for 2 hours under reflux, followed by cooling. The inorganic material is then filtered off with suction. The filtrate is evaporated in a vacuum, the evaporation residue is dissolved in about 250 ml. ethyl acetate and this solution is shaken up with 150 ml. aqueous 2N potassium carbonate solution and with sodium thiosulphate solution. The organic phase is separated off, dried and evaporated in a vacuum to give 21.7 g. crude 1-ethyl-3-nitro-4-pyrazole carbonitrile in the form of an oil. 15.7 g.<\/p>\n

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.<\/p>\n

Reference:
Patent; Boehringer Mannheim GmbH; US4105772; (1978); A;<\/a>,
Pyrazole – Wikipedia<\/a>,
Pyrazoles – an overview | ScienceDirect Topics<\/p>\n","protected":false},"excerpt":{"rendered":"

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[682,131],"tags":[126],"class_list":["post-4166","post","type-post","status-publish","format-standard","hentry","category-39205-87-3","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nSome tips on<\/title>\n<meta name=\"description\" content=\"Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 39205-87-3, name is 3-Nitro-1H-pyrazole-4-carbonitrile, A new synthetic method of this compound is introduced below., Formula: C4H2N4O2\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=4166\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Some tips on\" \/>\n<meta property=\"og:description\" content=\"Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. 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Pyrazole derivatives play an important role in antitumor agents.\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\",\"name\":\"Jessica.F\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"caption\":\"Jessica.F\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Some tips on","description":"Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. 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