{"id":4069,"date":"2021-05-14T08:49:37","date_gmt":"2021-05-14T00:49:37","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=4069"},"modified":"2021-05-14T08:49:37","modified_gmt":"2021-05-14T00:49:37","slug":"simple-exploration-of-948571-47-9","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=4069","title":{"rendered":"Simple exploration of 948571-47-9"},"content":{"rendered":"

Some common heterocyclic compound, 948571-47-9, name is 2-(4-Amino-1H-pyrazol-1-yl)ethanol, molecular formula is C5H9N3O, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. Quality Control of 2-(4-Amino-1H-pyrazol-1-yl)ethanol<\/a><\/p>\n

General procedure: A solution of compound 1 (0.15 mmol), 2 (0.1 mmol) and Et3N (20 mmol%) in DCM (1.0 mL) was reacted at room temperature for appropriate times (monitored by TLC). After removal of the solvent under reduced pressure, the crude product was purified directly by column chromatography on silica gel (hexanes\/EtOAc=5\/1-2\/1) to afford the desired products.<\/p>\n

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 948571-47-9, its application will become more common.<\/p>\n

Reference:
Article; Wang, Xiao-Wei; Li, Peng; Xiao, Hua; Zhu, Shi-Zheng; Zhao, Gang; Tetrahedron; vol. 67; 39; (2011); p. 7618 – 7621;<\/a>,
Pyrazole – Wikipedia<\/a>,
Pyrazoles – an overview | ScienceDirect Topics<\/p>\n","protected":false},"excerpt":{"rendered":"

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 948571-47-9, its application will become more common.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[648,131],"tags":[126],"class_list":["post-4069","post","type-post","status-publish","format-standard","hentry","category-948571-47-9","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nSimple exploration of<\/title>\n<meta name=\"description\" content=\"Some common heterocyclic compound, 948571-47-9, name is 2-(4-Amino-1H-pyrazol-1-yl)ethanol, molecular formula is C5H9N3O, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. 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